LeserTrlat syndrome is characterized by the sudden appearance of a large amount elements seborrheic keratosis. The associated with development malignant tumors internal organs. reason for probably production cytokines cells organs (transforming growth factor alpha (TGF-), epidermal (EGF), etc.) endogenous mediators that affect proliferation keratinocytes and cause rapid Currently, question para...

INTRODUCTION Teledermatology is been currently introduced as a diagnostic tool in the daily practice of the dermatologist. Many published works regarding teleconsult show the high sensitivity and economic saving of this technique as a diagnostic method. MATERIAL AND METHODS In this article we report our experience with nearly 1,000 teleconsults carried out in a period of two years, from Octob...

Dermatosis papulosa nigra (DPN) is a benign skin condition characterized by multiple, small, hyperpigmented macules and papules found on the malar areas of the face, neck, and trunk. It is almost always seen in the black population. Prevalence of DPN in the black population has been reported to be between 10% and 35%, with many patients noting a family history of the lesions and the number of l...

We report the case of a 79-year-old Caucasian man, who developed numerous pruritic seborrheic keratoses on his chest and back within one year. An underlying malignant disease was suspected. Upper and lower endoscopies were performed and the patient was diagnosed with adenocarcinoma of the ascending colon. We discuss the clinical significance of his cutaneous symptoms/signs, and review the medic...

The aetiology of seborrheic keratoses (SK), the most common benign epithelial tumours, and any relationship with malignancy are not yet known. As a protective anti-cancer mechanism, apoptosis reflects cellular loss as a reaction to proliferative activity. The objective of this study was to quantify apoptosis in different SK types (acanthotic, hyperkeratotic, reticulated, irritated and clonal) a...