Climate change has a complex effect on snow at the regional scale. The change in snow patterns under climate change remains unknown for certain regions. Here, we used high spatiotemporal resolution snow-related variables simulated by a weather research and forecast model (WRF) including snowfall, snow water equivalent and snow depth along with fractional snow cover (FSC) data extracted from Mod...

Streptococcal surface enolase (SEN) is a major plasminogen-binding protein of group A streptococci. Our earlier biochemical studies have suggested that the region responsible for this property is likely located at the C-terminal end of the SEN molecule. In the present study, the gene encoding SEN was cloned from group A streptococci M6 isolate D471. A series of mutations in the sen gene corresp...

Droughts affect human well-being and the economy of countries across world. Understanding long-term evolution droughts within a particular region will help in drought mitigation adaptation plans, thereby reducing impact on environment. This study examined multidecadal trends hydrological at two stations along River Niger using 3-month, 6-month, annual time scales. Hydrological events were ident...

Senecionine (SEN) is a representative of the hepatotoxic pyrrolizidine alkaloids. Although phase I metabolism for cytochrome P450-mediated metabolic activation of SEN was investigated extensively, phase II metabolism for glucuronidation of this compound has not been investigated until now. In our present study, one unique glucuronidation product of SEN in human liver microsomes (HLMs) was ident...

INTRODUCTION Subependymal nodule (SEN) and subependymal giant cell astrocytoma (SEGA) are brain lesions frequently found in tuberous sclerosis (TS). As about 10-15% of SENs enlarge and transform into SEGAs, we examined here the possible mechanism of the phenomenon. MATERIAL AND METHODS Using Western blot we studied 1 SEN and 3 SEGA samples; SEN and 1 SEGA came from the same TS patient. We eva...

Kendall Rank Correlation Let (X1, Y1), · · · , (Xn, Yn) be a bivariate random sample of size n. The Pearson correlation coefficient provides an optimal measure of the degree of association between the X’s and the Y ’s when the sample is drawn from a bivariate normal distribution. The Pearson correlation coefficient is reasonably robust for many other distributions as well. The Kendall correlati...

Chronic respiratory disorders such as asthma are believed to be associated with adverse cardiovascular events. We hypothesize that asthmatic inflammation translates into systemic inflammation and alters vascular responses where adenosine (AD) plays an important role. Therefore, this study investigated the effects of aerosolized AD, used to elevate lung AD levels, on vascular reactivity and infl...