BACKGROUND Wilson's disease is a rare but treatable condition that often presents diagnostic dilemmas. These dilemmas have for the most part not been resolved by the identification and cloning of the Wilson's disease gene. AIMS To report our experience over three decades with patients with Wilson's disease in order to illustrate the diverse patterns of presentation and thereby broaden the app...

BACKGROUND Liver transplantation is indicated for patients with Wilson's disease (WD) who present either with acute liver failure or with end-stage liver disease and severe hepatic insufficiency as the first sign of disease. However, almost all reported cases have been treated with death donor liver transplantation. Here we report the case of a patient with WD associated with fulminant hepatic ...

Wilson’s disease (WD) is an inherited disorder of copper metabolism. It results in copper deposition in toxic concentrations in liver, brain, eye, etc. Radiological features in the form of extensive gray and white matter abnormalities are rare. Here we report a case of WD presenting with encephalopathy and unusual radiological features. A 26-year-old male, born out of nonconsanguineous marriage...

We settle an open problem mentioned in Diaz, Petit, and Serna: A survey of graph layout problems (ACM Computing Surveys 34:313–356, 2002). Of eight objectives considered in that survey, only the complexity status of minimum vertex bisection is listed as unknown. We show that both minimum and maximum vertex bisection are NP-hard, but polynomially solvable on special graph classes such as hypercu...

Article history: Received 11 November 2007 Received in revised form 20 November 2008 Accepted 20 November 2008 Available online 11 December 2008 Communicated by R. Fleischer

1. FLEISCHER J., DEUCHERT M., RUHS C., KÜHLEWEIN HALVADJIYSKY G., SCHMIDT 2008, Design and Manufacturing of Micro Milling Tools, Microsyst. Technol., 14, 1771–1775. Google Scholar

Fleischer and Mannel (FM) have shown that it may become possible to constrain the angle γ of the unitarity triangle from measurements of various B → πK decays. This constraint is independent of hadronic uncertainties to the few percent level. We show that, within the Standard Model, the FM bound gives strong constraints on the CKM parameters. In particular, it could predict a well defined sign ...