conclusions according to the results of these work-ups, xla was diagnosed for the cases. introduction x-linked agammaglobulinemia (xla) is one of the primary humoral immunodeficiencies. it usually presents symptoms of recurrent infections, but in some unusual cases it may present rheumatologic manifestations. case presentation the current paper presents the cases of two boys with arthritis trea...

Although juvenile rheumatoid arthritis (JRA) was first described by Cornil (1864) and by Still (1897), the paediatrician often encounters aetiological, diagnostic, and prognostic problems. The purpose of the present follow-up study is to review our experience of this disease in recent years in an attempt to add to our knowledge of its natural history and in particular to clarify the long-term p...

T IS RECOGNIZED that tests for rheumaI toid factors are less often positive in juvenile rheumatoid arthritis (JRA) than in the adult form of the disease. The explanation for this discrepancy is not completely clear. Those children who develop seropositivity may constitute a separate group of patients from the standpoint of diagnosis or prognosis. Ideally, to ascertain this, children with arthri...

Our study of 1,254 patients with uveitis disclosed that nearly 10% had glaucoma as an additional visionrobbing feature of their disease, adding yet another dimension to the difficulties already posed by the inflammatory insult to the macula. Our data were similar to prior reports of the prevalence of glaucoma associated with selected specific uveitic entities.2-12 The prevalence has been especi...

BACKGROUND AND PURPOSE Juvenile rheumatoid arthritis (JRA) is the most common form of arthritis in children and affects both quality of life and school attendance. Weather and temperature conditions are believed to affect joint pains; however, very few studies have investigated this issue. This study examined the association between joint pain in JRA patients and weather conditions. METHODS T...

Historical background Rheumatologists have long known that the common chronic arthropathies of childhood have both similarities and differences from adult-onset rheumatoid arthritis (RA), although it is also recognized that a few patients with typical RA will present in childhood. Arthritis in children is more heterogeneous than RA, and just as in RA, the pathological basis for juvenile arthrit...

OBJECTIVE To assess parental distress, family functioning, and social support among parents of children with a lifetime diagnosis of juvenile rheumatoid arthritis (JRA) and comparison families. METHODS Parents of 64 children with JRA (64 mothers, 46 fathers) completed questionnaires and in-home interviews along with 64 matched comparison families. Average time since diagnosis for children wit...

Doctor Olson is with the Medical College of Wisconsin and Children’s Hospital of Wisconsin in Milwaukee, Wis. She has received funding from Amgen and Children’s Hospital Foundation. ABSTRACT Juvenile idiopathic arthritis (JIA) is the most common chronic arthropathy of childhood. Previous terminology identified this entity as juvenile rheumatoid arthritis. The 7 subsets of JIA identified under t...

Juvenile rheumatoid arthritis (JRA) is thought by many to be a different disease from rheumatoid arthritis in adults (RA), partly because of the infrequency of pathological serological phenomena (Calabro, 1966). Recent investigations have, however, shown that antigammaglobulin and antinuclear antibodies are often found in sera from patients with JRA (KAss and Munthe, 1969; Torrigiani, Ansell, C...