We investigated the involvement of the HRPT2 gene by loss of heterozygosity analysis and direct sequencing in a kindred with hyperparathyroidism-jaw tumor syndrome (HPT-JT) and three kindreds with familial isolated primary hyperparathyroidism (FIHP). Seven patients with sporadic parathyroid cancers and 35 with parathyroid adenomas with no family history of primary hyperparathyroidism or HPT-JT ...

LiNiO2 (LNO)基态的晶体结构和电子结构长期以来存在着实验与理论计算不一致的争议. 实验上观测到LNO是空间群为 $$R\overline3m$$ 的半导体并且有局部的Jahn-Teller (JT)畸变, 但理论计算却表明它是处于亚稳态的金属并且没有任何的JT畸变. 本文基于杂化密度泛函理论HSE06, 首次模拟了与实验等同浓度(~3%)的Ni/Li反位缺陷对LNO的影响, 发现缺陷能够有效调控LNO中的JT效应. 在LNO中引入Ni/Li反位缺陷后, 其结构发生了局部的JT畸变, 并且其带隙值约为0.5 eV, 这些计算结果都和实验现象非常吻合. Ni/Li反位通过粒径效应和库伦作用, 既能诱发JT畸变, 又能阻碍畸变之间的协同作用, 避免相变到C2/m, 而只产生局部的JT畸变. 本文提出了一种新的策略来解释LNO基态晶体结构和电子结构长期以来的争议, 对推动富镍层状材...

The extracts of Jerusalem thorn fruits (JT-FE) have been commonly used for the treatment diabetes mellitus in Turkey. In this study, it is aimed to investigate effects JT-FE, prepared by decoction, on blood glucose, insulin and glycated haemoglobin levels diabetic rats induced with streptozotocin (STZ). Hypoglycemic activity was examined streptozotocin-induced rats. For purpose, pre-prandial su...

BACKGROUND Papillary thyroid carcinoma (PTC) is often accompanied by lymph node metastasis (LNM), compared with follicular thyroid carcinoma (FTC). Sialic acid is carried by fibronectin (sFN) as the antigen of monoclonal antibody (MoAb) JT-95 detected in 90% of PTC, and a few cases of FTC. PATIENTS AND METHODS JT-95 staining was performed in 9 PTC and 20 follicular type tumors to investigate ...

Theorem 4.1.1 If OPT contains k sets, the greedy algorithm uses ≤ k(1 + ln nk ) sets. Proof: Let It be the sets selected by the greedy algorithm up to t iterations. Let nt be the number of uncovered elements at iteration t. Then nt = n− | ⋃ i∈It Si|, n0 = n, I0 = ∅. We claim that: Claim 4.1.2 nt ≤ (1− 1 k )nt−1 Proof: Let Jt = U\( ⋃ i∈It Si), then OPT covers Jt−1 with ≤ k sets. Because |Jt−1| =...

This study prospectively investigated 3,118 standard 12-lead ECGs recorded in 1,804 patients, who participated in the Losartan Heart Failure Survival Study--ELITE II clinical trial. After exclusion of patients with rhythms other than sinus, or atrioventricular block, or poor quality ECGs, 986 (703 men, mean age 71 +/- 7 years) with baseline ECGs were retained, of whom 615 patients had follow-up...

CDC73 (HRPT2) germline mutations are responsible for more than half of cases of hyperparathyroidism-jaw tumor syndrome (HPT-JT) and for a subset of familial isolated HPT (FIHP). We performed a clinical, genetic, and histopathologic study in three unrelated Italian kindreds with HPT-JT and FIHP. We identified three germline inactivating mutations of the CDC73 gene in the probands and affected pa...

AIMS This study was designed to test the hypothesis that acute psychological stress is capable of inducing an increase in the dispersion of repolarization in patients with underlying coronary artery disease. METHODS AND RESULTS Twenty four patients undergoing elective coronary angiography were studied, 17 with significant coronary artery disease and seven with normal coronary arteries. Follow...

This paper reports recent R&D results on negative ion-based NBI for JT-60SA where 10 MW neutral beam is designed to inject for 100 seconds. There are major two issues such as improvement of voltage holding capability and reduction of the grid power loading of the JT-60U negative ion source with three acceleration stages. To improve the voltage holding capability, the breakdown location with the...

The so-called Jar Test (JT) plays a vital role in the drinking water and wastewater treatments for establishing the dosage of flocculants and coagulant. This test is a well-proved laboratory instrumental procedure performed by trained personnel. In this work, a completely novel system for the automation and monitoring of a JT devoted to drinking water treatment is presented. It has been impleme...