Children with juvenile rheumatoid arthritis (JRA) report poor sleep quality, daytime sleepiness, fatigue, anxiety, and altered mood. Sleep disturbances in school-aged children are an issue of serious concern. Children are at an age when sleep is of primary importance to physical and intellectual growth, and sleep disturbances that begin in childhood may persist into adulthood. In this article w...

OBJECTIVE To evaluate sensitivity of arthrosonography of hip and knee joints for monitoring disease activity in juvenile rheumatoid arthritis (JRA). METHODS Twenty eight patients with JRA with active disease at entry in 15 hips and 38 knee joints were followed up three times in intervals of 4-6 weeks. Sonographic, clinical, and laboratory findings were documented at the same time in clinicall...

Abstract We investigate historical regional climate changes in Japan from 1959 to 2020, analyzing a high-resolution dynamical downscaling forced by the Japanese 55-year Reanalysis (JRA-55). One-year continuous simulations are conducted non-hydrostatic model with land surface that includes snow accumulation process, which enables us evaluate seasonal variation of cover all Japan. Our simulation ...

Background: Antiphospholipid antibody syndrome (APS) can either occur as a primary syndrome or associated with other autoimmune diseases such as systemic lupus erythematosus (SLE). Anticardiolipin antibody (aCL) of IgG and/or IgM isotype in blood, measured by a standardized ELISA is the most acceptable laboratory criteria. APS IgG isotype, particularly IgG2 subclass is more strongly associated ...

The aetiology of juvenile rheumatoid arthritis (JRA) is unknown. All epidemiological attempts to prove a genetic background or familial predisposition were inconclusive. The three recent studies of monozygotic, demonstrated a high incidence of rheumatoid arthritis among patients' relatives. An indirect evidence for genetic predisposition was suggested by Howard and Ansell (1964), who found a hi...

Abstract Based on daily data from the Japanese 55-year Reanalysis (JRA-55) covering spring seasons 1958 to 2018, this study examines formation mechanisms and climate impacts of springtime western Pacific (WP) pattern as subseasonal variability over North Pacific. Results suggest that WP arises a weak dipole-like disturbance disturbances East Asia. The energetic analysis suggests baroclinic ener...

Abstract. A major strong sudden stratospheric warming (SSW) occurred in the Southern Hemisphere (SH) stratosphere 2002 (hereafter referred to as SSW2002), which is one of most unusual winters SH. Following several warmings, polar vortex broke down midwinter. Eastward-traveling waves and their interaction with quasi-stationary planetary played an important role during this event. This study anal...

Abstract. Global reanalyses from data assimilation systems are among the most widely used datasets in weather and climate studies, potential vorticity (PV) is invaluable for many studies of dynamical transport processes. We assess how consistently modern represent each other, focusing not only on PV but also process-oriented diagnostics including equivalent latitude calculated PV-based tropopau...

Abstract. The sea level over the tropical Pacific is a key indicator reflecting vertically integrated heat distribution ocean. Here, we use Geophysical Fluid Dynamics Laboratory global ocean–sea ice model (GFDL-OM4) forced by both Coordinated Ocean-Ice Reference Experiment (CORE) and Japanese 55-year Reanalysis (JRA-55)-based surface dataset for driving models (JRA55-do) atmospheric states (Oce...

OBJECTIVE Juvenile rheumatoid arthritis (JRA), also known as juvenile idiopathic arthritis (JIA), is a rare autoimmune joint disorder of children. The concrete causes for the prevalence of the above pathological state are still unknown. In other words, it is an arthritis affecting mainly children and adolescents. Clinically, it has 3 different clinical subtypes. JRA patients are often noticed w...