Background and Aim: The reduction of temporomandibular joint disorders (TMD) is one of the most significant concerns in dentistry. In contrast to initial treatments, such as pharmacotherapy and physiotherapy, which act as temporary tranquilizers, growth factors have shown promising results in the stimulation of cell division. Given the limited research on the positive impact of platelet-rich pl...

OBJECTIVE To verify the biologic links between progressive cellular and structural alterations within knee joint components and development of symptomatic chronic pain that are characteristic of osteoarthritis (OA), and to investigate the molecular basis of alterations in nociceptive pathways caused by OA-induced pain. METHODS An animal model of knee joint OA pain was generated by intraarticu...

PURPOSE Although disease progression of osteoarthritis has been well documented, pain pathophysiology is largely unknown. This study was designed with two purposes: 1) to characterize patients with knee pain predominantly originating from intra-articular structures and 2) to describe the location and pattern of their pain. MATERIALS AND METHODS 103 patients with medial knee osteoarthritis und...

Joint pain is a common presenting symptom seen in the outpatient setting. Accurate diagnosis is imperative for providing optimal patient care. Our patient is a 50 year old male who presented with many years of joint pain affecting multiple joints. He was diagnosed with seronegative Rheumatoid arthritis. Despite treatment with immunosuppressive medications, his joint symptoms persisted and he de...

CONTEXT Facet or zygapophysial joint blocks are used extensively in the evaluation of chronic spinal pain. However, there is a continuing debate about the value and validity of facet joint blocks in the diagnosis of chronic spinal pain. The value of diagnostic facet joint injections may have been overlooked in the medical literature. OBJECTIVES To determine the accuracy of facet joint blocks ...

APTA is a sponsor of the Decade, an international, multidisciplinary initiative to improve health-related quality of life for people with musculoskeletal disorders. A lthough some people in the medical community accept the premise that the sacroiliac joint (SIJ) can be a source of pain secondary to pathology (eg, spondyloarthropathy, infection, malignancy, fracture),1 whether SIJ dysfunction ex...

OBJECTIVE Regarding the efficacy of joint lavage in the treatment of knee OA, we evaluated reports of randomized controlled trials (RCTs) to assess the efficacy of joint lavage alone or joint lavage combined with IA steroid injection to alleviate pain and improve function in knee OA. METHODS We searched MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials for all reports pub...

BACKGROUND Chronic sacroiliac (SI) joint pain constitutes 16% to 30% of the total prevalence of chronic low back pain, which is commonly unilateral. Apart from conservative management, various interventional pain management procedures have been reported. Intraarticular deposteroid injection has been described as the most evidence-based, but different various radio frequency (RF) procedures have...