INTRODUCTION Cancer in the parathyroid gland is rare, but parathyroid cancer is occasionally seen in relation to genetic abnormalities. Due to a limited amount of evidence, the optimal handling of these cases is not clear. Furthermore, the presence of a malignant parathyroid tumor is rarely known at the time of the initial operation; therefore, re-operations are often necessary. The aim of this...

Ameloblastoma is a slow-growing and locally invasive epithelial odontogenic tumor of the jaw that runs benign course in most cases. Granular cell ameloblastoma rare subtype ameloblastoma, showing granular transformation its cytoplasm. It considered as an aggressive variant ameloblastoma. Herein, we report case 34-year-old male patient who presented with swelling left cheek for 1-year duration r...

CONTEXT Parafibromin, encoded by HRPT2, is the first marker with significant benefit in the diagnosis of parathyroid carcinoma. However, because parafibromin is only involved in up to 70% of parathyroid carcinomas and loss of parafibromin immunoreactivity may not be observed in all cases of HRPT2 mutation, a complementary marker is needed. OBJECTIVE We sought to determine the efficacy of incr...

Abstract— Dental radiographs are essential in diagnosing the pathology of the jaw. However, similar radiographic appearance of jaw lesions causes difficulties in differentiating cyst from tumor. Therefore, we conducted a development of computer-aided classification system for cyst and tumor lesions in dental panoramic images. The proposed system consists of feature extraction based on texture u...

introduction: myxomas are a group of benign rare tumors of connective-tissue origin that occur in both hard (central) and soft tissues of the body. the aim of this study is to highlight our experience in the management of central myxoma of the jaw, with emphasis on its clinic-epidemiologic features as seen in our environment.  materials and methods: all patients who were managed for central myx...

Oral squamous cell carcinoma (OSCC) cells display significantly augmented nuclear factor-κB (NF-κB) activity, and inhibiting this activity suppresses malignant tumor characteristics. Thus, we evaluated the effect of IMD-0560, a novel inhibitor of IκB kinase (IKK) β that is under assessment in a clinical trial of rheumatoid arthritis, on bone invasion by the mouse OSCC cell line SCCVII. We exami...

Objectives: The continuous increase in the incidence of oral squamous cell carcinoma (OSCC) in young patients is more often confronting the surgeon with the question of how aggressive the surgical therapy should be, particularly in terms of lymph node dissection. This retrospective study presents data from young patients focusing on the occurrence of cervical metastasis (CM) and the prognosis. ...

Skeletal manifestations of primary hyperparathyroidism (pHPT) include brown tumors (BT), which are osteoclastic focal lesions often localized in the jaws. Brown tumors are a rare manifestation of pHTP in Europe and USA; however, they are frequent in developing countries, probably related to vitamin D deficiency and longer duration and severity of disease. In the majority of cases, the removal o...

Toothache of a lower primary molar followed by bilateral swelling of the lower molar regions were the first symptoms of a 6-year-old Finnish male with Burkitt-type malignant lymphoma. Radiographic examination revealed osteolytic changes in the right mandibular and left maxillary quadrant. The cortical bone around the affected teeth was absent and some teeth were grossly displaced. When the ther...