Disruption of blood-brain barrier is a common brain injury in intracerebral hemorrhage. Sufentanil an analogue fentanyl, and acts as opioid analgesic postsurgical analgesia anaesthesia. also exerted neuroprotective effect against cerebral infarction. The role sufentanil hemorrhage (ICH)-induced was investigated. Firstly rat model established by local injection collagenase IV into striatum. Rats...

PURPOSE To compare the outcomes such as postoperative nausea/vomiting, analgesic requirements, and hospital stay following the use of topical oxybuprocaine hydrochloride 0.4% or intravenous (IV) fentanyl in children undergoing strabismus surgery. METHODS This was a prospective cohort study. Children operated under general anesthesia for strabismus were given topical oxybuprocaine hydrochlorid...

Endotracheal intubation, a common procedure in newborn care, is associated with pain and cardiorespiratory instability. The use of premedication reduces the adverse physiological responses of bradycardia, systemic hypertension, intracranial hypertension and hypoxia. Perhaps more importantly, premedication decreases the pain and discomfort associated with the procedure. All newborn infants, ther...

Objective: Our study compared the effect of fentanyl alone with fentanyl plus intravenous ketorolac for analgesic efficacy, opioid sparing effects, and opioid-related side effects after laparoscopic cholecystectomy. Materials and Methods: Sixty patients undergoing laparoscopic cholecystectomy were randomized into two groups. Both groups received fentanyl during induction. First group of patient...

BACKGROUND People with special needs undergoing dental surgery frequently require general anesthesia. We investigated the effect of remifentanil vs fentanyl on stress response and postoperative pain in people with special needs undergoing day-case dental surgery. METHODS Forty-six adult patients with cognitive impairment undergoing day-case dental surgery under general anesthesia were allocat...

conclusions the addition of ketamine to intravenous fentanyl plus acetaminophen pca had not extra effects in relieving post abdominal surgery pain. results there were no significant demographic differences between two groups. pain scores (at rest, while moving and coughing) during the first 48 hours were not significantly different between two groups (p values = 0.361, 0.367 and 0.204, respecti...

BACKGROUND Emergence agitation (EA) in children after sevoflurane anesthesia is common. The purpose of this study was to compare the incidences of EA between ketamine and thiopental sodium induction in children underwent sevoflurane anesthesia. We also evaluated if a small dose of fentanyl could reduce the incidence of EA. METHODS The patients who were scheduled for strabismus or entropion su...

OBJECTIVE To compare the effects of fentanyl or remifentanil in combination with midazolam on hemodynamic parameters, pain, and satisfaction profile in cataract surgery. METHODS This randomized, double blind, prospective study was conducted between 10 and 20th July 2005 at Kudret Eye Hospital, Ankara, Turkey. Patients scheduled for cataract surgery by the phacoemulsification technique were ra...