Herpes zoster most commonly occurs in elderly patients, and usually affects sensory neurons. Therefore, its characteristic symptoms are segmental pain, itching, and sensory changes in the affected areas. A 71-yr-old woman experienced painful herpetic rash on the right cervical 2-4 dermatomes for 16 days. Two days after the onset of the rash, she was diagnosed with herpes zoster, and prescribed ...

Sunburn, wound repair, and chronic renal failure with hemodialysis are usually accompanied by both pigmentation and itching. Proopiomelanocortin-derived α-melanocyte-stimulating hormone (α-MSH) is produced in response to external stimuli, such as UV irradiation, and is involved in cutaneous pigmentation. However, it is unclear whether α-MSH is also involved in the itching. We therefore investig...

BACKGROUND The main objective of this randomized, double-blind, parallel-group, comparative study was to assess the efficacy and safety of rupatadine 10 mg (R10) and 20 mg (R20) administered once-daily for two weeks compared with those of loratadine 10 mg (L10) in the treatment of seasonal allergic rhinitis (SAR). METHODS A total of 339 SAR patients were randomized to receive R20 (111 patient...

BACKGROUND The purpose of this study was to evaluate the efficacy and duration of action of once-daily dosing with alcaftadine 0.25% ophthalmic solution and olopatadine 0.2% ophthalmic solution as compared with placebo in the prevention of ocular itching, and to directly compare the efficacy of alcaftadine 0.25% with olopatadine 0.2% in the prevention of ocular itching associated with allergic ...

Background Allergic rhinitis (AR) is a multifaceted condition affecting up to 40% of the population. AR leads to nasal symptoms of congestion, rhinorrhea, sneezing, and nasal itching. It is often associated with ocular symptoms of itching/burning, tearing/watering and redness. AR has a negative impact on patients’ quality of life (QoL) due to both nasal and ocular symptoms. Market research show...

Progressive pigmentary purpura or Schamberg's disease. Pigmented purpuric lichenoid dermatitis of Gougerot and Blum red/brown papules and plaques in men which responds to psoralen combined with ultraviolet A (PUVA) treatment. Purpura annularis telangiectodes rare, with a preponderance in young females and manifests as annular erythematous plaques and patches. Eczematoid-like purpura of Doucas a...