Hydrogen and carbon isotope ratios of cellulose nitrate and oxygen isotope ratios of cellulose from C(3), C(4), and Crassulacean acid metabolism (CAM) plants were determined for plants growing within a small area in Val Verde County, Texas. Plants having CAM had distinctly higher deuterium/hydrogen (D/H) ratios than plants having C(3) and C(4) metabolism. When hydrogen isotope ratios are plotte...

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In sickle cell anemia (SCA), the loss of reticuloendothelial function is the result of vasoocclusive events occurring in the spleen. Such asplenia occurs early in the course of the disease and is considered to be permanent in late childhood. In this report, three patients 10, 11, and 14 years of age suffering from severe SCA and found to be asplenic were treated by bone marrow transplantation (...

• Multi-Element Analysis Introduction Laser ablation inductively coupled plasma-mass spectrometry (LA-ICP-MS) has developed over recent years to become a sophisticated tool for the multielemental and isotope ratio analysis of solid samples. Besides a true multi-elemental capability, independent of matrix, the major requirements for most geological laser applications in ICP-MS are the highest se...

Mrs. L., a 51 year old housewife, presented with a 2 cm. lump in the left breast, which she had first noticed three months previously. Excision biopsy revealed a very poorly differentiated adenocarcinoma with tumour in adjacent vessels. When radiotherapy was instituted 3 weeks later she complained of shortness of breath on exercise, and a dry cough. Over the following week she became increasing...

The use of agents that decrease bone resorption, notably the calcitonins, diphosphonates and mithramycin, has been shown to result in symptomatic and/or biochemical improvement in patients with Paget's disease of bone (osteitis deformans). The effects of short-term (6 months), low-dose (5 mg/kg body mass/d) etidronate disodium, a diphosphonate compound at present subject to registration in this...

A bleeding Meckel's diverticulum is presented in a 4-month-old African American infant. This event is rare at this age, and our patient is only the second 4-month-old infant reported in the English literature. The infant presented with painless frank rectal bleeding, the blood being maroon-colored, and clots were found in the diaper. There was also anemia, with an hemoglobin of less than 8 gm/d...

Literature data on H /D isotope effects on polarizability are reviewed. An argument based on perturbation theory correlates the isotopic differences with electronic transition moments via vibra­ tional averaging. The contribution of the second moment isotope effect is especially important. The approach is first illustrated with a calculation on H 2/D 2 and then employed to correlate differentia...