The hypotensive effect of garlic has been well-documented in human subjects and animals. Since endothelial activity regulates vascular reactivity in physiological and pathophysiological conditions, the aim of the present study was to investigate the effect of garlic on endothelium-dependent and independent relaxation of rat aorta for elucidation of mechanism of the garlic anti-hypertensive effe...

In the structure of the title salt, C6H16N2 (2+)·2NO3 (-), the cations are connected to the anions through bifurcated N-H⋯(O,O) and weak C-H⋯O hydrogen bonds, generating corrugated layers parallel to the (100) plane. The organic cation is centrosymmetric and the diprotonated piperazine ring adopts a chair conformation, with the methyl groups occupying equatorial positions.

In this lecture, we develop the notion of “adaptive learning” as proposed by Milgrom and Roberts [1]. Although the learning definition they give is of interest in its own right, it primarily derives power in the case of dominance solvable games, or for games where there is a straightforward characterization of the set of strategies surviving iterated strict dominance (hereafter ISD). Throughout...

Hughes S: Effect of prazosin vs placebo on chronic left ventricular heart failure. Circulation 59: 344, 1979 12. Curtiss C, Cohn JN, Vrobel T, Franciosa JA: The role of the renin-angiotension system in the systemic vasoconstriction of chronic heart failure. Circulation 58: 763, 1978 13. Packer M, Meller J, Gorlin R, Herman MW: Hemodynamic and clinical tachyphylaxis to prazosin-mediated afterloa...

The hemodynamic and antianginal effects of 30 mg of isosorbide dinitrate (ISDN) were assessed in 12 patients with chronic stable angina after initial dosing and after 7 to 10 days of therapy four times daily. During early therapy, ISDN produced significant hemodynamic and antianginal effects that persisted over a 3 hr observation period. During sustained therapy there was attenuation of the hem...

Objective The aim of this study was to evaluate the evidence for Shexiang Baoxin Pill (SBP) and isosorbide dinitrate (ISDN/Xiaoxintong) use in angina of coronary heart disease. We compared their efficacy in effect rate in angina relief (included significant effect and normal effect) and electrocardiogram (EGC) improving rate. Methods Systematically searched Randomized Control Trials (RCTs) in t...

OBJECTIVES Comparison of effects of propofol and isosorbide dinitrate during rewarming on cardiopulmonary bypass in patients undergoing coronary artery bypasses grafting. METHODS It was randomized prospective clinical trial. One hundred and twenty patient (120) undergoing CABG surgery were included in this study. Group-I (Study group, n=60): in which only propofol infusion used during rewarmi...

OBJECTIVE To examine the pressure gradient and peripheral fractional flow reserve (pFFR) measured by a pressure wire as indicators of hemodynamic significance in iliofemoral angiographic intermediate stenosis. BACKGROUND The utility of pressure measurements using a pressure wire with vasodilators is unclear in cases with intermediate iliofemoral stenosis. METHODS The mean pressure gradient ...