www.thelancet.com Vol 384 October 11, 2014 1345 as 1–2% chlorhexidine in isopropyl alcohol, but we agree with Maiwald and colleagues that adequate studies to support or reject this hypothesis have not yet been done. Chlorhexidine in an alcoholic solution, however, is clearly superior to povidone-iodine for prevention of vascular catheter-related bloodstream infec tion. Maiwald and colleagues ha...

Based on ursolic acid, 3 compounds with isothiocyanate groups located at different distances from C-17 of the triterpenoid core have been synthesized through ursane-derived primary amines. To obtain terpene hybrids thioureas and N,S-containing heterocycles, series amines ammonia were reacted novel isothiocyanates. In reactions propargylamine, 4,5-dihydrothiazol-2-yl-amine selectively obtained i...

In a double-blind study the fiberoptic bronchoscope was contaminated with five pathogenic organisms, each at a concentration of 10(9) organisms per milliliter. The shaft and inner channel of the bronchoscope were cleansed with five antiseptic regimens. Each regimen included equal 120-ml aliquots of one, two, or three solutions, respectively. The five different regimens were as follows: (1) phys...

A purified alkaline thermo-tolerant bacterial lipase from Bacillus cereus MTCC 8372 was immobilized on a Poly (MAc-co-DMA-cl-MBAm) hydrogel. The hydrogel showed approximately 94% binding capacity for lipase. The immobilized lipase (2.36 IU) was used to achieve esterification ofmyristic acid and isopropanol in n-heptane at 65 degrees C under continuous shaking. The myristic acid and isopropanol ...

The data in this article shows the effect of isopropyl myristate (IPM) on a 2D Stratum Corneum lipid model. In the first part, the analytical characterization of the synthesized deuterated isopropyl myristate is given. Then a BAM image of the pure Stratum Corneum model used is shown and a dataset of surface-pressure - area isotherms considering various ratios of deuterated and non-deuterated IP...

PURPOSE. Effects of cis-unoprostone isopropyl, its primary metabolite M1, trans-unoprostone isopropyl, latanoprost free acid, and fluprostenol were studied on Ca2þ-activated Kþ (BK) channels, plasma membrane potential, [cAMP]i, [cGMP]i, and steady state [Ca]i, and protection against endothelin-1 (ET-1)– induced steady state [Ca]i increases in human cortical neuronal (HCN-1A), trabecular meshwor...

The title compound, C(19)H(31)O(2)P, features a distorted tetra-hedral P atom that bonds to the phenyl ring, isopropyl and 2-isopropyl-5-methyl-cyclo-hexyl groups, and is determined as having an R(p) configuration. A chair conformation is observed for the cyclo-hexyl ring. In the crystal, mol-ecules are linked into chains running along the a axis by weak inter-molecular C-H⋯O hodrogen bonds.