Registry No. HRU~(~-COM~)(CO)~~, 71737-42-3; HRuzOs(pCOMe)(CO)lo( C1 isomer), 116079-24-4; HRuOS2(p-COMe) (CO) (C, isomer), 116079-25-5; HOS~(~-COM~)(CO)~~, 69048-01-7; H3Ru3(p3-COMe)(CO)s, 71562-47-5; H3R~205(p3-COMe)(C0)9, 116079-26-6; H3R~O~2(p3-COMe)(CO)e, 116079-27-7; H3Ru20s(p3-COMe)(C0)7(AsPh3)2, 116079-28-8; H3RuOs2(p3-COMe)(CO)8(AsPh3), 116079-29-9; H3R~20s(~3-COMe)(CO)8(AsPh3), 116079...

3'-Azido-3'-deoxythymidine triphosphate (erythro) and its threo isomer were synthesized and investigated for their inhibition of HIV reverse transcriptase from virus isolate U 937/HTLV-III. The erythro isomer was a competitive inhibitor of the reaction directed by (rA)n(dT)12-18 and the Ki value was 0.0022 microM. The threo isomer was at least 100-fold less active. The inhibition was specific f...

We report a joint experimental and theoretical study of CO chemisorption on the golden cages. We find that the Au(17)(-) cage is highly robust and retains its cage structure in Au(17)(CO)(-). On the other hand, the Au(16)(-) cage is transformed to a structure similar to Au(17)(-) upon the adsorption of CO. Au(18)(-) is known to consist of two nearly degenerate structures, i.e., a cage and a pyr...

The Gd(Be,α3n)Dy reaction has been used to study high-spin states in Dy. Pulsed beam conditions were utilised for enhanced isomer sensitivity. An isomer at 2188.1(3) keV with a half-life of 8.3(3) μs has been discovered and assigned K= 8 with a 2-quasineutron configuration. Among eleven γ-ray decay branches, an E2, ∆K= 8 transition to the ground-state band was observed with a reduced hindrance ...

The L isomer of (Y , y-diaminobutyric acid is a major component of the polymixin group of antibiotics (1) and of certain Lathyrus peas (24). Some of the polymixins alsocontain~-a:,y-diaminobutyric acid (1). Although the L acid appears to be neurotoxic in rats, it may not be the neurotoxic agent of human lathyrism (4). Except for distribution and toxicity studies in mice (5, 6) and uptake studie...

Insulin-like growth factor I (IGF-I or somatomedin C) is a serum polypeptide with three intramolecular disulfide bonds. In the course of synthesis by the recombinant DNA method, three disulfide bond isomers, all of which have Cys18-Cys61 with three combinations of two disulfide bonds formed by Cys6, Cys47, Cys48 and Cys52, were identified. Natural type, isomer II, was proved to have a Cys6-Cys4...

Photoresponsive systems for site-selective RNA scission have been prepared by combining Lu(III) ions with acridine/azobenzene dual-modified DNA. The modified DNA forms a heteroduplex with substrate RNA, and the target phosphodiester linkages in front of the acridine residue is selectively activated so that Lu(III) ion rapidly cleaves the linkage. Azobenzene residue introduced adjacent to the ac...

It has been previously reported that the main diene-conjugated fatty acid in human plasma is a non-oxygen containing linoleic acid isomer (PL-9, ll-LA’). It has also been proposed that this isomer can be used as a specific marker of free radical-mediated lipid peroxidation in humans. Here we report that the in vitro induction of lipid peroxidation in human and rat blood with either W irradiatio...

The recently reported heteroleptic cyclometallated iridium(III) complex [Ir(2-phenylpyridine)(2)(2-carboxy-4-dimethylaminopyridine)] N984 and its isomer N984b have been studied more in detail. While photo- and electrochemical properties are very similar, DFT/TDDFT calculations show that the two isomers have different HOMO orbital characteristics. As a consequence, solution processed OLEDs made ...

Neutron-rich nuclei in the lead region, beyond N = 126, have been studied at the FRS-RISING setup at GSI, exploiting the fragmentation of a primary uranium beam. Two isomeric states have been identified in 210Hg: the 8 isomer expected from the seniority scheme in the νg9/2 shell and a second one at low spin and low excitation energy. The decay strength of the 8 isomer confirms the need of effec...