نتایج جستجو برای: ischemic kidney injury
تعداد نتایج: 573979 فیلتر نتایج به سال:
Acute kidney injury induced by ischemia/reperfusion (IR) is a frequent complication in hospitalized patients. Mineralocorticoid receptor antagonism has shown to be helpful against renal IR consequences; however, the potential benefit of novel nonsteroidal mineralocorticoid receptor antagonists such as finerenone has to be further explored. In this study, we evaluated the efficacy of finerenone ...
Acute renal failure and tubular cell loss as a result of ischemia constitute major challenges in renal pathophysiology. Increasing evidence suggests important roles for bone marrow stem cells in the regeneration of renal tissue after injury. This study investigated whether the enhanced availability of hematopoietic stem cells, induced by stem cell factor and granulocyte colony-stimulating facto...
Abstract Background and purpose: Ischemia-reperfusion (I/R) is present at various degrees in kidney transplants. Several studies suggest that renal ischemia reperfusion (RIR) can induce acute kidney injury. Olive leaf is a significant source of bioactive phenolic compounds. They have better antioxidant capacity, anti-inflammatory and radical scavenging. Materials and methods: In this study ...
Earlier intervention after acute kidney injury would promote better outcomes. Our previous study found that Wnt proteins are promptly upregulated after ischemic kidney injury. Thus, we assessed whether Wnt4 could be an early and sensitive biomarker of tubular injury. We subjected mice to bilateral ischemia/reperfusion injury (IRI). Kidney and urinary Wnt4 expression showed an early increase at ...
introduction: cisplatin is used as a chemotherapeutic agent for the treatment of human ovarian and testicular cancers. this study was designed to investigate the protective role of taurine against cisplatin-induced kidney injury. methods: male wistar rats were divided into 4 groups (n=8) (1) saline-treated group (2) cisplatin-treated group (10 mg/kg, i.p.), (3) group that received taurine (200 ...
ARTICLES DISCUSSED: Aomatsu, A. et al. A quantitative detection method for microRNAs in the kidney of an ischemic injury mouse model. Journal Visualized Experiments. (163), e61378 (2020). Bauer, S., Pauli, J., Pelisek, J. Optimized high quality DNA extraction from formalin-fixed paraffin-embedded human atherosclerotic lesions. (168), e61452 (2021). Suárez-Cuenca, Predicting amputation using loc...
Abstract Background and Aims Acute Kidney Injury (AKI) is a critical condition that caused by the absence of oxygen during acute ischemic phase, leading to energy metabolism disturbance kidney tubular epithelial cell damage. Fatty Acid Oxidation (FAO) main source production renal proximal cells. Timely promoting FAO, increasing supplies energy, proliferation are essential improve injury. Howeve...
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