The goal of this study was to examine the relationships between 2 age-sensitive indices of brain integrity--volume and iron concentration--and the associated age differences in memory performance. In 113 healthy adults (age 19-83 years), we measured the volume and estimated iron concentration in the hippocampus (HC), caudate nucleus (Cd), and primary visual cortex (VC) in vivo with T2* relaxati...

Aspirin is being increasingly prescribed for cardiovascular protection, but is also recognized to have significant gastrointestinal side-effects. Whether chronic aspirin consumption causes iron deficiency is undetermined, and there is little information available regarding iron deficiency and aspirin use in old age. We studied the relationship between iron deficiency anaemia and regular aspirin...

Background: Iron overload is caused early progression of atherosclerosis in beta thalassemia patients due to regular repeated blood transfusion. MRI T2* is a gold standard non-invasive method for detecting hepatic and cardiac iron overload. The aim of this study was the comparison of carotid intima media thickness (CIMT) in the patients and healthy control groups with Doppler ultrasound for ear...

Iron is necessary for life but also a potent pro-oxidant implicated in the pathogenesis of age-related diseases. We sought to determine if iron levels change with age and by sex in various tissues from several commonly studied mouse strains. Brain, liver, heart, retina, and retinal pigment epithelium (RPE)/choroid were dissected from male and female mice of young adult (2-6 month old) and aged ...

BACKGROUND The Australian Iron Status Advisory Panel advocates dietary intervention as the first treatment option for mild iron deficiency [serum ferritin (SF) = 10-15 microg/L]. However, there appear to be no studies on the efficacy of dietary treatment for iron deficiency. OBJECTIVE We compared the effects of iron supplementation and of a high-iron diet on serum ferritin (SF) and hemoglobin...

Currently, there are some 222 records in the Nottinghamshire Sites and Monuments Record (SMR) which are relevant to the First Millennium B.C. These records include 19 finds of Late Bronze Age metalwork, 5 examples of Iron Age metalwork, 9 find-spots of Iron Age coins, 57 find-spots of pottery ascribed to the Late Bronze Age and Iron Age, 21 finds of other objects ascribed to these two periods, ...

The reviewed volume is one output of the Interreg DTP Monumentalized Early Iron Age Landscapes in Danube river basin (acronym Iron-Age-Danube) program, which involved professionals from Austria, Croatia, Hungary, Slovakia and Slovenia.

(1) Background: Iron requirement increases during pregnancy and iron supplementation is therefore recommended in many countries. However, excessive iron intake may lead to destruction of pancreatic β-cells. Therefore, we aim to test if higher neonatal iron content in blood is associated with the risk of developing type 1 diabetes mellitus (T1D) in childhood; (2) Methods: A case-control study wa...

BACKGROUND Can exclusive breastfeeding until six months of age maintain optimum iron status in term babies? We evaluated iron status of exclusively breastfed term infants in relation to breast milk iron and lactoferrin. METHODS In this prospective study in Delhi, India, during the period 2003-2004 normally delivered babies of non-anemic [(Hemoglobin (Hb) = 11 g/dl, n = 68] and anemic (Hb 7 - ...

OBJECTIVE The objective was to determine the prevalence of iron deficiency and iron deficiency anemia among exclusively breastfed infants from one to six months of life and to identify associated risk factors. METHODS This is a cohort study of the hemoglobin and serum ferritin levels of 102 healthy full-term infants, weighing more than 2500 grams (5.5 pounds) at birth, evaluated for growth de...