When defining the balance between tumor control and toxicities, considerable caution must be exercised near organs with serial functional subunits, such as the spinal cord and named nerves, because of the potential for irreversible damage. In such challenging clinical scenarios, the highly targeted nature of intraoperative radiation therapy (IORT) may offer a viable option to improve patient ou...

BACKGROUND To date, there are no reports of intraoperative radiotherapy (IORT) use with long-term follow up as a method of accelerated partial breast irradiation (APBI) in Asian countries. We initiated a prospective phase I/II clinical trial of IORT in Japan in 2007, and herein, we report the 5-year follow-up results. MATERIALS AND METHODS The following inclusion criteria were used for enroll...

The control and transmission of huge data constitute an immense challenge in various types networks (wired wireless). Congestion caused by the high traffic low throughput continues to be major problems a heterogeneous platforms such as internet things (IoT) technology internet-of-robotic-things (IoRT). network requires new models mechanisms deal with increased challenges posed IoT IoRT. Accordi...

PURPOSE To retrospectively evaluate the results after a regimen of surgery, IORT (intraoperative radiotherapy), and EBRT (external beam radiotherapy) for soft-tissue sarcomas METHODS 38 consecutive patients underwent IORT for soft-tissue sarcoma; 29 were treated for primary tumours, 9 for recurrences. There were 14 cases with liposarcomas, 8 with leiomyosarcomas, 7 with malignant fibrous hist...

AIM The investigation of the irradiation time calculation accuracy of the GGPB algorithm used for IORT. BACKGROUND Conventionally, breast conserving therapy consists of breast conserving surgery followed by postoperative whole breast irradiation and boost. The use of intraoperative radiotherapy (IORT) enables the boost to be delivered already during the surgery. In this case, the treatment do...

intraoperative radiation therapy (iort) is a multidisciplinary approach in which residual tumors or tumor beds are directly irradiated during a surgical procedure. to evaluate its efficacy, from 1985, we conducted a prospective study including non-metastatic gastric adenocarcinoma treated by surgery, iort (15 grays) and postoperative external beam radiotherapy (44 grays). up to 1993, 51 cases o...

The objective of this study was to evaluate the safety, effectiveness and functional outcomes of intraoperative radiotherapy (IORT) followed by intensity-modulated radiation therapy (IMRT) in locally advanced stage tumours involving the middle ear. Data on 13 consecutive patients treated for malignant tumor of external auditory canal involving the middle ear were retrospectively reviewed. Media...

Recently, two pivotal papers with Intraoperative radiotherapy (IORT) are published [1,2]. The standard treatment for early breast cancer is breast-conserving therapy (BCT) with whole breast external irradiation therapy (WBI) [3]. Even in highly selected patients, omission of radiotherapy increases the risk of local recurrence [4]. In actuality some women are still encouraged to proceed to maste...

In patients with low-risk breast cancer, intraoperative radiotherapy (IORT) during breast-conserving surgery is a novel and convenient treatment option for delivering a single high dose of irradiation directly to the tumour bed. However, edema and fibrosis can develop after surgery and radiotherapy, which can subsequently impair quality of life. TGF- β is a strong inducer of the extracellular m...

Internet of Robotic Things (IoRT) is a new concept introduced for the first time by ABI Research. Unlike the Internet of Things (IoT), IoRT provides a dynamic actuation and is considered as the new evolution of IoT. This new concept will bring new opportunities and challenges, while providing new business ideas for IoT and robotics’ entrepreneurs. In this work, we will focus particularly on two...