Alex Avdeef [1] and Samuel Yalkowsky [2] have independently studied the solubility and ionization properties of an investigational drug (NSC-639829). In the study conducted by Avdeef and coworkers, the pKa value derived from Henderson-Hasselbalch (HH) equation was 4.70, which was different from the value of 3.76 as determined experimentally by the Yasuda-Shedlovsky plot using the pKa values obt...

The partial photoionization cross sections and asymmetry parameters of S atoms have been measured using constant-ionic-state (CIS) spectroscopy in the photon energy range 10.0-30.0 eV. The ionizations investigated in these CIS experiments are the (3p)(-1) ionizations S(+)((4)S)<--S((3)P), S(+)((2)D)<--S((3)P), and S(+)((2)P)<--S((3)P). For the first time Rydberg series which converge to the fou...

T h e method of CERMAK and HERMAN has been appl ied to mass spectrometr ic studies of symmetrical electron and proton transfer processes. The characteristics of the ion source used have been investigated both experimental ly and theoretical ly. A new type of ionization ef f ic iency curve is obtained if the current of a secondary ion is plotted as a funct ion of the voltage between ionization c...

Recent STIS and FUSE observations have detected O VI absorption lines at low redshift that are not clearly associated with any galactic system. In this paper, we argue that these lines are due to metal enriched hot gas in the intergalactic medium. Using numerical simulations of a cosmological-constant dominated cosmology, combined with reasonable assumptions about the metallicity distribution, ...

IJalld-st.ruct urc, ollect s ha.ve been incorporated in the framework of {.he SphericalIIarnlol~ics k;xpansion ( S H E ) of the Boltz~nann Transport Equat.ion ( B T E ) for ~lcctrons ill silicon [ I ] , using t.he densit,y of st.at.es ( D O S ) and the group velocity ( C V ) obt.ained from t,he full-band syst.em [2]. In t,his paper an impactionizat.ion model is present,ed along wit,h the numeri...

We have determined for the first time the equilibrium constant, Keq, for the reaction of Ellman's reagent, 5,5'-dithiobis(2-nitrobenzoate), with the CysF9[93]beta sulfhydryl groups of the hemoglobins of the domestic cat. In the pH range 5.6 to 9.0 Kequ varies over four orders of magnitude--between ca 10 and 10(-3)--for all hemoglobin derivatives. Using these Kequ values and published data on th...

The general coupling between particle transport and ionization-recombination processes in hot plasma is considered on the key concept of equilibrium charge state (CS) transport. A theoretical interpretation CS gained terms a two-dimensional (2D) Markovian stochastic (random) processes, discrete 2D Fokker-Plank-Kolmogorov equation (in space variables) generalized coronal atomic basic tool for an...

The new platelet antiaggregant Triflusal or 2-acetoxy-4-trifluoromethylbenzoic acid presents a structural analogy to acetylsalicylic acid (ASA). Alkaline hydrolysis of triflusal was studied in the presence and absence of cationic micelles of N-cetyl-N-ethyl-N,N-dimethylammonium bromide (CDEABr) at different KOH concentrations and different temperatures (25, 30, and 37 degrees C) using a spectro...