OBJECTIVES There is concern that hydrogen peroxide generated by tooth bleaching agents may cause enhanced metal ion release (including mercury) from dental amalgam following contact. The aim of this in vitro study was therefore to investigate the effect of a carbamide peroxide (CP) based tooth bleaching gel on metal ion release from dental amalgam. METHODS Dental amalgam discs were prepared a...

The ryanodine receptor channel is an intracellular membrane Ca2+-release channel. The investigation of ion translocation and discrimination in individual channels under voltage-clamp conditions has revealed that the channel can sustain very high rates of cation translocation, has high affinity for divalent cations and displays relatively poor discrimination between physiologically relevant cati...

Ca depletion/Interphase death/Rat thymocytes Role of Ca ion in development of radiation damage of rat thymocytes was examined. Free DNA release, an expression of chromatin degradation, and the percentage of erythrosin B stained (dead) cells were increased after incubation of 1000 R X-irradiated thymocytes with normal Ca-containing medium. Incubation of the irradiated cells with Ca ion-depleted ...

cium was omitted from the medium, and markedly inhibited by the addition of cocaine. 3. Addition of reserpine or tyramine stimulated the release of catecholamine from the slices. The effect of reserpine was diminished in calcium free medium, but that of tyramine was not affected in calcium free medium. Cocaine had a weak inhibitory effect on the release of catecholamine caused by reserpine but ...

The effects of coenzyme Q10 (Co Q10) on potassium ion release, membrane potential and fluidity of rabbit red blood cells were studied. Co Q10 inhibited the increased potassium ion release induced by cetylamine or lysolecithin from the cells. Co Q10 slightly decreased the membrane potential monitored by changes in fluorescence intensity of cyanine dye, 3,3'-dipropyl-2,2'-thiodicarbocyanine iodid...