conclusions combination therapy with surgical excision has a synergistic effect and appears to be the best treatment for extended lesions. however, new potent antibacterial drugs may help to improve the management of such infections when there are sufficient data on their in vitro activity. introduction nocardia species are described as opportunistic pathogens that mainly cause pulmonary nocard...

conclusions midazolam could be used as a safe and effective drug for conscious sedation, general anaesthetic premedication and the treatment of seizures during dental treatment. however, further research on paediatric patients would be beneficial. evidence acquisition to conduct this review of the literature, pub-med and scopus were searched using the following terms: midazolam, oral, transmuco...

Among a large group of users of illicit intravenous drugs, the incidence of bullous pulmonary damage was noted to be 2 percent (6/387). Bullous damage was significantly different in the drug users than in those who did not use drugs. The drug users were significantly younger than the nonusers, their bullae were large and confined to the upper lobes, and alpha 1-antitrypsin deficiency was very u...

Background: Intravenous drug delivery is an advantageous choice for rapid administration, immediate drug effect, and avoidance of first-pass metabolism in oral drug delivery. In this study, the synthesis, formulation, and characterization of atorvastatin-loaded polyurethane (PU) nanoparticles were investigated for intravenous route of administration. Method: First, PU was synthesized and charac...

Avascular necrosis (AVN) of the femoral head is an emerging complication in HIV infected patients. It has been suggested that the increased incidence of AVN in this population may be caused by an increased prevalence of predisposing factors for osteonecrosis, including protease inhibitors, hyperlipidemia, corticosteroid use, alcohol and intravenous drug abuse. The aim of this study was to asses...