نتایج جستجو برای: intrahepatic sickling

تعداد نتایج: 12228  

Journal: :The Journal of clinical investigation 1981
L R Berkowitz E P Orringer

Cetiedil has been reported to relieve painful crises in sickle cell anemia and to have antisickling properties in vitro. The drug alters neither oxygen affinity nor the solubility of deoxyhemoglobin S. Because the viscosity of the erythrocyte interior and the kinetics of gelation are dependent on the concentration of hemoglobin, we postulated that cetiedil might inhibit sickling by modifying er...

2017
Mukund P Kulkarni

Intrahepatic pseudocyst of pancreas is a very rare entity and a significant diagnostic dilemma with less than 30 cases reported in the world literature. Demonstration of amylase rich fluid and a communication with pancreatic duct system establishes the diagnosis. There are no definite guidelines for the management. Here we describe a patient with alchohol related chronic pancreatitis with pseud...

Journal: :Journal of General Physiology 1955

Journal: :Blood 1964
S CHARACHE C L CONLEY

By SAMUEL CIIARAcIIE AND C. LOCKARD CONLEY S ICKLED ERYTHROCYTES are rapidly removed for the circulation, an occurrence that accounts for the hemolytic aspects of sickle cell disease.’ Anemia is a usual result but is often asymptomatic and is not the principal cause of the high morbidity and reduced life span of affected persons. Many of the clinical manifestations of sicklemia have been attrib...

Journal: :Blood 1961
M AKSOY

I ‘ ‘ HAS been known for sonic tulle that the Eti-Turks pOSSCSS tile iligheSt incidence of sickling in the white race.’ Several previous papers have diScussed the characteristics of these people and have described the incidence of abnormal genes responsible for thalassemia and abnormal hemoglohins.25 It was also pointed out in some of these i tpers that tile Eti-Turks and the Allewits of Syria ...

2003
H. Joiner

Deoxygenation-induced cation movements in sickle cells were inhibited 80% to 85% by the anion transport inhibitor, 4,4’-diisothiocyano-2,2’disulfostilbene (DIDS). Morphologic sickling was not altered by DlDS treatment, demonstrating that morphologic sickling was not sufficient to produce cation leaks in sickle cells. DlDS inhibition of deoxygenationinduced cation flux was not affected when Irep...

Journal: :Blood 1968
T H Ham R F Dunn R W Sayre J R Murphy

A SERIES OF STUDIES is reported on changes in physical properties of red cells that indicate abnormalities in their rigidity or deformability. Increased rigidity is a term used to describe changes in red cells leading to increased viscosity of flow, a shift to more Newtonian type of flow and lack of deformability as measured by packing under centrifugal force or by diminished flow through micro...

Journal: :Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2015
Hajime Matsushima Tamotsu Kuroki Amane Kitasato Tomohiko Adachi Takayuki Tanaka Masataka Hirabaru Takanori Hirayama Naoki Kuroshima Masaaki Hidaka Akihiko Soyama Mitsuhisa Takatsuki Naoe Kinoshita Kazunori Sano Noriyuki Nishida Susumu Eguchi

BACKGROUND Intrahepatic cholangiocarcinomas develop through a multi-step carcinogenesis. Precancerous lesions are defined as biliary intraepithelial neoplasia. Sex determining region Y-box9 (Sox9) is required for the normal differentiation of the biliary tract. AIMS To evaluate the Sox9 expression in carcinogenesis and its correlation with clinicopathological features in intrahepatic cholangi...

Journal: :Science 1950
H A HANNO M P MARGOLIES

Enzymic Conversion of Maltose into Unfermentable Carbohydrate: S. C. Pan, A. A. Andreasen, and Paul Kolachov.115 Activation of Arginase in Vitro by Mouse Carcass Extract and the Cobalt Ion: 0. B. Wiswell .117 Further Study of the Role of Hyaluronidase in the Fertilization of Rabbit Ova in Vivo: M. C. Chang ...... ........................... 118 A Simple Staining Technique for Detecting Virus Di...

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