نتایج جستجو برای: interferon lambda 3

تعداد نتایج: 1887222  

2013
Janett Fischer Stephan Böhm Tobias Müller Heiko Witt Christoph Sarrazin Simone Susser Pascal Migaud Eckart Schott Graeme Stewart Annika Brodzinski Balazs Fülöp Florian van Bömmel Jacob George Thomas Berg

BACKGROUND & AIMS Genetic variations near the interferon lambda 3 gene (IFNL3, IL28B) are the most powerful predictors for sustained virologic response (SVR) in patients with chronic hepatitis C virus (HCV) infection, compared to other biochemical or histological baseline parameters. We evaluated whether the interplay of both IFNL3 polymorphisms rs12979860 and rs8099917 together with non-geneti...

Journal: :Journal of virology 2015
Ma Del Rocío Baños-Lara Lindsey Harvey Alexander Mendoza Dawn Simms Vladimir N Chouljenko Nobuko Wakamatsu K Gus Kousoulas Antonieta Guerrero-Plata

UNLABELLED Human metapneumovirus (hMPV) is a respiratory paramyxovirus that is distributed worldwide and induces significant airway morbidity. Despite the relevance of hMPV as a pathogen, many aspects of the immune response to this virus are still largely unknown. In this report, we focus on the antiviral immune response, which is critical for viral clearance and disease resolution. Using in vi...

Journal: :The Journal of Experimental Medicine 1990
T J Vasicek P Leder

We determined the DNA sequence of two large regions of chromosome 22: 33.7 kb containing the C lambda complex; and 5.2 kb 5' of the functionally rearranged lambda gene from the human myeloma, U266. Analysis of these sequences reveals the complete structure of the human C lambda complex and a previously undescribed seventh C lambda region that may encode the Ke+Oz- lambda protein. The seven cons...

Journal: :Physical review. E, Statistical, nonlinear, and soft matter physics 2007
Zhenhua Wu Cecilia Lagorio Lidia A Braunstein Reuven Cohen Shlomo Havlin H Eugene Stanley

We propose numerical methods to evaluate the upper critical dimension d(c) of random percolation clusters in Erdös-Rényi networks and in scale-free networks with degree distribution P(k) approximately k(-lambda), where k is the degree of a node and lambda is the broadness of the degree distribution. Our results support the theoretical prediction, d(c) = 2(lambda - 1)(lambda - 3) for scale-free ...

Journal: :Physical review letters 2006
Manoj Gonuguntla Ashutosh Sharma Jayati Sarkar Subash A Subramanian Moniraj Ghosh Vijay Shenoy

Based on experiments and 3D simulations, we show that a soft elastic film during adhesion and debonding from a rigid flat surface undergoes morphological transitions to pillars, labyrinths, and cavities, all of which have the same lateral pattern length scale, lambda close to lambda/H approximately 3 for thick films, H > 1 microm . The linear stability analysis and experiments show a new thin f...

Journal: :caspian journal of mathematical sciences 2014
s‎. ‎khademloo f. yosefzade

‎in this paper‎, ‎we study a class of boundary value problem‎ ‎involving the p-laplacian oprator and singular nonlinearities‎. ‎we‎ ‎analyze the existence a critical parameter $lambda^{ast}$ such‎ ‎that the problem has least one solution for‎ ‎$lambdain(0,lambda^{ast})$ and no solution for‎ ‎$lambda>lambda^{ast}.$ we find lower bounds of critical‎ ‎parameter $lambda^{ast}$‎. ‎we use the method ...

Majdi El Ghord Makkia Dammak,

In this paper, we investigate the existence of positive solutions for the ellipticequation $Delta^{2},u+c(x)u = lambda f(u)$ on a bounded smooth domain $Omega$ of $R^{n}$, $ngeq2$, with Navier boundary conditions. We show that there exists an extremal parameter$lambda^{ast}>0$ such that for $lambda< lambda^{ast}$, the above problem has a regular solution butfor $lambda> lambda^{ast}$, the probl...

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