نتایج جستجو برای: interchromosomal effect
تعداد نتایج: 1642066 فیلتر نتایج به سال:
The mammalian cell nucleus provides a landscape where genes are regulated through their organization and association with freely diffusing proteins and nuclear domains. In many cases, specific genes are highly dynamic, and the principles governing their movements and interchromosomal interactions are currently under intensive study. Recent investigations have implicated actin and myosin in chro...
Johannes et al. (1) recently presented interesting new data on the LET dependence of intrachromosomal aberration yields, which may be compared with earlier theoretical calculations and experimental results. Specifically, Johannes et al. reported that their measured ratios of intrachromosomal to interchromosomal aberrations were independent of LET, in contrast to some in vitro measurements (2), ...
The etiology of mental retardation (MR), often presenting as developmental delay in childhood, is unknown in approximately one-half of cases. G-banding is the standard method for investigating those suspected of having a chromosomal etiology; however, detection of structural abnormalities is limited by the size and pattern of the G-bands involved. Rearrangements involving subtelomeric regions h...
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