This report has been prepared by Mitretek systems for the Intelligent Transportation Systems (ITS) Joint Program Office Of the Federal Highway Administration (FHWA). The report documents the first phase of an investigation of how to " mainstream " , or integrate, ITS planning into general transportation planning at the state, regional and local levels. Specifically described are the processes b...

To meet Energy Independence and Security Act (EISA) cellulosic biofuel mandates, the United States will require an annual domestic supply of about 242 million Mg of biomass by 2022. To improve the feedstock logistics of lignocellulosic biofuels in order to access available biomass resources from areas with varying yields, commodity systems have been proposed and designed to deliver quality-cont...

Abstract This study aims to design a route optimization model support commodity distribution in the Moluccas archipelago zone. The is designed using an integer programming approach for multi-depot multi-cluster with aim of minimizing distance. In this case, several points on island must be serviced. Each service point will only choose one port serve. Sea transportation routes are formed from se...

In real-world express systems, couriers need to satisfy not only the delivery demands but also pick-up of customers. Delivery and pickup tasks are usually mixed together within integrated routing plans. Such a problem can be abstracted formulated as Vehicle Routing Problem with Mixed Pickup (VRPMDP), which is an NP-hard combinatorial optimization problem. To solve VRPMDP, there three major chal...

BACKGROUND Risperidone long-acting injectable (RLAI), the first second-generation depot antipsychotic, has extensively been studied before introduction. Thereafter, questions about the type of patients actually treated with RLAI in daily practice remain to be answered for making valid antipsychotic treatment comparisons involving RLAI in observational studies. OBJECTIVE We aimed to determine ...

This paper studies approximations to the average length of Vehicle Routing Problems (VRP) with time window, route duration, and capacity constraints. The approximations are valuable for the strategic and planning analysis of transportation and logistics problems. Using asymptotic properties of vehicle routing problems and the average probability of successfully sequencing a customer with time w...

The virtual warehouse (VW) is a state of real-time global visibility for logistics assets such as inventory and vehicles. The eciency of the VW is comparable to that achieved in a local warehouse facility. We assess the enabling technologies, develop a conceptual framework, and identify the essential decisionsupport modules of a virtual warehouse. A case study for ®eld repair service illustrat...

This paper studies the multi-objective pickup and delivery problem with time windows (PDPTW), in which a fleet of homogeneous vehicles with the same capacities located in a depot serve a collection of given transportation requests. Each request is composed of a pickup location, a delivery location and a given load. The PDPTW is to determine a vehicle scheduling strategy with the objectives of m...

Improving outcomes in schizophrenia generally requires an improvement in medication adherence. One of the most effective interventions to improve adherence is the use of depot formulations of antipsychotic medications. A new depot aripiprazole formulation for the treatment of schizophrenia will be available soon. A review of all publically available information on depot aripiprazole as of Novem...