Particulate microemboli and in vitro platelet aggregation were studied in blood of patients during cardiac operations with an electronic particle size analyzer. A small gradient of microemboli developed on passage of blood through a bubble oxygenator but not through a membrane oxygenator. However, with both types of oxygenators, there was a sustained increase in the volume of microemboli in car...

Concentrated growth factors are extracted from platelet-rich plasma obtained healthy adult veins by physical gradient centrifugation, and the activated platelets release various cytokines, which can be further converted into concentrated liquid or gel preparations different centrifuge tubes. These widely used in clinical treatments fields, such as dentistry, dermatology surgery. In this article...

Proteomics has provided powerful new insights into the complex events of the anucleate platelet and has revealed many potential protein targets in the search for suitable agents for thrombotic disease. In the present study, we summarize recent proteomic approaches to analyse specific platelet subproteomes, such as the platelet releasate, the platelet phosphotyrosine proteome and characterizatio...

Rapid occlusion of artificial microvascular grafts (AMGs; less than or equal to 2-mm diameter) by platelet-rich thrombi prevents the clinical use of AMGs in cardiac, vascular, and plastic surgery. Since present antiplatelet agents are unable to assure AMG patency, we have studied the role of specific platelet membrane-glycoprotein blockade on platelet retention by AMGs. In a customized in vitro...

Periodontal problems have a high prevalence in the general population, these are characterized by loss of attachment, resulting most inferior position free gingival margin, on any part exposed root surface. It may be present both arches, buccal and lingual surfaces, teeth. With advancement techniques advances achieved through technology, with aim optimizing physiological phenomenon healing, add...

Tumor cell adhesion to subendothelial matrix in the presence of platelets and plasma has been examined in vitro using an entirely homologous system of rat Walker 256 carcinosarcoma cells, matrix laid down by rat aortic endothelial cells and rat platelets and plasma. In the presence of platelets or platelets plus plasma, tumor cell adhesion was significantly enhanced when compared to adhesion in...