RATIONALE Chronic obstructive pulmonary disease (COPD) is a common, complex multisystem disease in the elderly with multiple comorbidities that significantly impact morbidity and mortality. Although cerebral small-vessel disease is an important cause of cognitive decline and age-related disability, it is a poorly investigated potential systemic manifestation of patients with COPD. OBJECTIVES ...

BACKGROUND Brain microbleeds (BMBs) detected on gradient echo T2*-weighted magnetic resonance imaging (GE-MRI) may be pathophysiologically linked to ischemic cerebral small-vessel disease (SVD) and increased risk of future hemorrhagic stroke. Chronic kidney disease (CKD) has been associated with the presence of BMBs in stroke patients. However, the relationship between CKD markers and BMBs in s...

Majority of ependymomas are infratentorial and intraventricular. Supratentorial and purely cortical extraventricular ependymomas are extremely rare and only five cases were reported. We report a 15-year-old male with left frontal cortical ependymoma. He had gross total excision of the lesion and was not given radioptherapy.

Abstract Objective: Brainstem, pontine, and cerebellar (infratentorial) stroke has been associated with motor cranial nerve dysfunction. However, case reports clinical observations suggest that cognitive impairment may be present. Acute inpatient rehabilitation is a critical time to implement interventions; however, intervention opportunities missed if providers are unaware of dysfunction do no...

Abstract Background Contrast-enhancing (CE) lesions are an important finding on brain magnetic resonance imaging (MRI) in patients with multiple sclerosis (MS) but can be missed easily. Automated solutions for reliable CE lesion detection emerging; however, independent validation of artificial intelligence (AI) tools the clinical routine is still rare. Methods A three-dimensional convolutional ...

Brain tumors represent the most common solid neoplasm in children and second most common pediatric malignancy overall, following leukemia. Outside of infancy, the majority of primary childhood brain tumors occur in the infratentorial compartment and include medulloblastoma, juvenile pilocytic astrocytoma (JPA), ependymoma, and brainstem/ pontine glioma; atypical teratoid rhabdoid tumor (ATRT) i...