نتایج جستجو برای: inflammatory antioxidant

تعداد نتایج: 344321  

2011
Boris V Nemzer Liliana C Rodriguez Linda Hammond Robert DiSilvestro John M Hunter Zbigniew Pietrzkowski

BACKGROUND Measuring the effects of the acute intake of natural products on human biomarker concentrations, such as those related to oxidation and inflammation, can be an advantageous strategy for early clinical research on an ingredient or product. METHODS 31 total healthy subjects were randomized in a double-blinded, placebo-controlled, acute pilot study with post-hoc subgroup analysis on 2...

2015
José Luis Rodríguez-Chávez Elvia Coballase-Urrutia Antonio Nieto-Camacho Guillermo Delgado-Lamas

It has been suggested that the accumulation of biomolecular damage caused by reactive oxygen species (ROS) contributes to aging. The antioxidant activity is related to the ability of certain compounds to protect against the potentially harmful effect of processes or reactions involving ROS. This ability is associated with the termination of free radical propagation in biological systems. From H...

2011
Ingrid Emerit

The plasma of patients with hepatitis C contains chromosome-damaging substances, the so-called "clastogenic factors" (CFs), as this is the case for other chronic inflammatory diseases and after radiation exposure. These endogenous clastogens, formed as a consequence of increased superoxide production by inflammatory cells, can be detected with cytogenetic methods, as they are used for exogenous...

2014
DEEPTI DIXIT ANKITA JOSHI DEEPAK BHATNAGAR

Objective: Vitex negundo, commonly known as “nirgundi” is widely used in traditional as well as in folk medicines to cure many ailments such as fever, rheumatism, gum and skin diseases and liver disorders, etc. The present study evaluated the antioxidant potency of hydroethanolic extract of Vitex negundo leaves (VNE) in Freund’s complete adjuvant (FCA) induced arthritis. Methods: Acute oral tox...

Journal: :Journal of agricultural and food chemistry 2013
Diana González-Peña Clara Colina-Coca Cielo D Char M Pilar Cano Begoña de Ancos Concepción Sánchez-Moreno

The flavonol content and anti-inflammatory and antioxidant activities of onion treated by high-pressure processing (HPP) and HPP combined with freeze-drying and pulverization (HPP-FD-P) were evaluated. Allium cepa L. var. cepa, 'Recas' was treated at T1 (200 MPa/25 °C/5 min), T2 (400 MPa/25 °C/5 min), and T3 (600 MPa/25 °C/5 min). After treatment, HP-treated and untreated samples were frozen (d...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد علوم دارویی - پژوهشکده علوم 1392

purpose a metabolic abnormality such as obesity is a major obstacle in the maintenance of the human health system and causes various chronic diseases including type 2 diabetes, hypertension, cardiovascular diseases, as well as various cancers. this study was designed to summarize the recent scientific knowledge regarding the anti-obesity role of curcumin (diferuloylmethane), which is isolated f...

Journal: :Iraqi Journal of Pharmaceutical Sciences 2023

Background: Acute lung injury (ALI) is among the most serious conditions characterized by an exacerbation of inflammatory response that can result from a persistent infection. Carvone chiral monoterpenoid ketone present in essential oils dill, caraway, and spearmint. It shows antioxidant, anti-inflammatory, antimicrobial effects others. In this study, anti-inflammatory protective potential mech...

Journal: :Biochemical and biophysical research communications 2010
David Adenuga Samuel Caito Hongwei Yao Isaac K Sundar Jae-Woong Hwang Sangwoon Chung Irfan Rahman

Abnormal lung inflammation and oxidant burden are associated with a significant reduction in histone deacetylase 2 (HDAC2) abundance and steroid resistance. We hypothesized that Nrf2 regulates steroid sensitivity via HDAC2 in response to inflammation in mouse lung. Furthermore, HDAC2 deficiency leads to steroid resistance in attenuating lung inflammatory response, which may be due to oxidant/an...

2016
Shi-Xun Wang Jian Wang Jing-Bo Shao Wei-ning Tang Jing-Quan Zhong

BACKGROUND Plumbagin is a potent antioxidant with anti-inflammatory and anti-carcinogenic action. Myocardial ischemia/reperfusion injury results in organ damage through oxidative stress and inflammatory mechanisms. In this study, we analyzed the potential role of plumbagin against myocardial I/R injury in Wistar rats. MATERIAL AND METHODS Oxidative stress was measured through ROS, lipid peroxid...

Antje Huefner, Ataa Said, Elsayed A Abuotabl Gehan Fawzy Abdel Raoof, Somaia A Nada

Objective(s): This study aimed to develop drugs from natural sources to overcome the side effects of many of synthetic drugs. Methanol extracts of both pericarp and seeds of Pleiogynium solandri were used to investigate antioxidant, hepatoprotective, and renal function protective, analgesic, and anti-inflammatory effects and to determine the chemical composition of the extract responsible for b...

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