Peptidyl arginine deiminase (PAD)4 is a nuclear enzyme that catalyzes the posttranslational conversion of arginine residues to citrulline. Posttranslational protein citrullination has been implicated in several inflammatory autoimmune diseases, including rheumatoid arthritis, colitis, and multiple sclerosis. Here, we tested the hypothesis that PAD4 contributes to ischemic acute kidney injury (A...

The size of stemflow infiltration areas around the boles trees is currently a topic interest and debate within hydrologic community. There gap in our knowledge many wooded ecosystems need for more than few studies that have examined directly. Hence, this field study was specifically undertaken to mitigate existing data by providing direct measurements from high stemflow-producing American beech...

The human cytokine, interferon-inducible protein-l0 (IP-101, is a small glycoprotein secreted by activated monbcpes, T cells, keratinocytes, astrocytes, and endothelial cells and is structurally related to the a subfamily of chemotactic cytokines caled chemokines (Taub and Oppenheim, Cytokine 5175, 1993). However, in contrast to other a chemokines that induce neutrophil migration, IP-10 has bee...

BACKGROUND AND AIMS The shortage of organs for transplantation has led to increased use of organs procured from donors after cardiac death (DCD). The effects of cardiac death on the liver remain poorly understood, however. Using livers obtained from DCD versus donors after brain death (DBD), we aimed to understand how ischemia/reperfusion (I/R) injury alters expression of pro-inflammatory marke...

The ability of macrophages to cause acute inflammatory glomerular injury is well-established; however, the role of macrophages in the fibrotic phase of chronic kidney disease remains poorly understood. This study examined the role of macrophages in the fibrotic phase (days 14 to 35) of established crescentic glomerulonephritis. Nephrotoxic serum nephritis (NTN) was induced in groups of eight Wi...

infiltration is a complex process that changed by initial moisture and water head on the soil surface. the main objective of this study was to estimate the coefficients of infiltration equations, kostiakov-lewis, philip and horton, and evaluate the sensitivity of these equations and their coefficients under various initial conditions (initial moisture soil) and boundary (water head on soil surf...

The Iztaccíhuatl-Popocatépetl National Park is a remnant of high-mountain conifer forests and grasslands that provides ecosystem services to Mexico City. This research assesses the impact constructing ditches, through modeling infiltration, soil erosion, carbon sequestration with hydrological model SWAT, based on information (bulk density, organic carbon, depth) obtained from ditches. resulting...

 Background: Tissue injuries may provoke neuro-hormonal response which in turn may lead to release of inflammatory cytokines. We hypothesize that block of afferent sensory pathways by infiltration of 0.5% bupivacaine in the scalp may decrease neuro-hormonal response in the neurosurgical patient. Methods: After obtaining informed consent, forty ASA physical statuses I, II, or III patients betwee...

plant cover is one of the most important factors affecting infiltration rate of water into the soil and decreasing runoff. distribution of plants in arid and semi-arid areas is almost patchy and form different patterns. one of the fascinating patterns is ring-shaped growth pattern. ring patterns of varying size are formed by clonally reproducing grasses, sedges and even shrubs growing in resour...