BACKGROUND Area under the concentration-time curve (AUC) is a pharmacokinetic parameter that represents overall exposure to a drug. For selected anti-infective agents, pharmacokinetic-pharmacodynamic parameters, such as AUC/MIC (where MIC is the minimal inhibitory concentration), have been correlated with outcome in a few studies. A limited-sampling strategy may be used to estimate pharmacokine...

The effects of different application technologies were evaluated on the concentration, viability, and effi ciency of infective juveniles of the nematodes Heterorhabditis indica Poinar, Karunakar & David and Steinernema sp. (IBCB-n6) to control Spodoptera frugiperda Smith on corn plants. Two hundred and eighty infective juveniles of Steinernema sp. were required to kill 100% third-instar fall ar...

Blood transmitted infection is the commonest cause of death after blood transfusion. All patients on regular packed cell volume (PCV) or any blood component are at increased risk of transfusion transmitted infections. The etiological agents can be virus, bacteria or protozoa. These organisms can cause clinical sickness in recipient, can persist in him as carrier state or can cause asymptomatic ...

INTRODUCTION The aim of this study was to analyze a PCR based approach for detection of infective endocarditis in Azerbaijan. METHODS Ten aortic valves, 8 mitral valves and 2 tricuspid valves, were analyzed for the presence of bacterial infective endocarditis using Gram staining, culture and PCR methods. RESULTS Of the 20 valves, 5 and 4 cases were positive by Gram staining and culture assa...

Infective endocarditis is a common clinical problem in industrialized countries. Risk factors include abnormal cardiac valves, a history of endocarditis, intracardiac devices, prosthetic valves and intravenous drug use. We report a case of polymicrobial infective endocarditis in a 33 year-old female with a history chronic heroin use caused by Neisseria sicca and Haemophilus parainfluenzae. We b...

infective endocarditis can complicate with ischemic stroke. neurological complications develop in 20-40% of all patients with infective endocarditis. these are mainly due to vegetation embolism.this report represents a case of 30 years old female patient who presented with features of heart failure new york heart association (nyha) class iv with infective endocarditis and left hemiparesis. on e...