Most studies of infectious diseases in East African cattle have concentrated on gastro-intestinal parasites and vector-borne diseases. As a result, relatively little is known about viral diseases, except for those that are clinically symptomatic or which affect international trade such as foot and mouth disease, bluetongue and epizootic haemorrhagic disease. Here, we investigate the seroprevale...

Herpesvirus infections of domestic ruminants are about economic losses due to respiratory and reproductive problems. Bovine herpesvirus 1 (BHV-1) is a major pathogen of bovines world-wide and causes different clinical manifestations including infectious bovine rhinotracheitis (IBR), infectious pustular vulvovaginitis (IPV) / balanopostitis (IPB) and meningoencephalitis [3]. These conditions are...

BACKGROUND In order to optimise the cost-effectiveness of active surveillance to substantiate freedom from disease, a new approach using targeted sampling of farms was developed and applied on the example of infectious bovine rhinotracheitis (IBR) and enzootic bovine leucosis (EBL) in Switzerland. Relevant risk factors (RF) for the introduction of IBR and EBL into Swiss cattle farms were identi...

Infectious bovine rhinotracheitis (IBR) is a viral disease caused by bovine herpesvirus-1 (BHV-1). It is a virus that mainly displays respiratory and genital tropism. However, for French farms, infection usually remains asymptomatic and this disease is first and foremost a trade issue. Listed in the Animal Health Code of the OIE (World Organisation for Animal Health), it has also given rise to ...

Clinical symptoms from the respiratory tract were observed in cattle after the introduction of pregnant heifers into the dairy herd. Sera and nasal swabs from all animals and tissue samples from two dead animals were tested for BHV1. Specific antibodies against BHV1 were found in serum samples of 24 animals. Only one sample reacted doubtfully in gB ELISA. The virus was isolated only from nasal ...

The antiviral activity of several ether derivatives of 5-hydroxymethyldeoxyuridine against the herpesvirus of infectious bovine rhinotracheitis was determined in monolayer cultures of secondary bovine fetal kidney cells. 5-Methoxy-methyldeoxyuridine (OCH(3)UdR) was found to be markedly inhibitory against this virus. Pretreatment of the cells with OCH(3)UdR, simultaneous addition of OCH(3)UdR wi...

365 sera samples were collected during 1997 from two groups of camels in Sharkia governorate, Egypt. The first group: 190 sera samples collected from slaughtered camels at Belbas abattoir, while the second group: 175 sera samples collected from individual camels which were in contact with cattle herds. Sera samples were tested by serum neutralization test for the presence of antibodies against ...