Many microRNAs (miRNAs) are selectively expressed in mammalian immune cells and have been linked to responses host defense autoimmune disease. In macrophages, miRNAs regulate cell metabolism by repressing the expression of genes such as transcription factors, enzymes, metabolism-related molecules, well that impact inflammatory phenotype determination. Previous studies showed miR-22 plays a role...

Pain and depression are frequently co-existent in clinical practice, yet the underlying mechanisms remain largely to be determined. Microglia activation and subsequent pro-inflammatory responses play a crucial role in the development of neuropathic pain and depression. The process of microglia polarization to the pro-inflammatory M1 or anti-inflammatory M2 phenotypes often occurs during neuroin...

nanostructured alumina thin films were coated on stainless steel by sol-gel dip coating method. in order to prevent crack formation, al2o3 films were kept in a solvent bath immediately after coating to reduce the rate of drying. effects of calcination temperature and withdrawal speed on structural properties were analyzed using xrd and sem. topography and thickness of coatings were analyzed by ...

the effect of chloride ions concentration on the electrochemical behavior of aisi 410 stainless steel in thesimulated concrete pore (0.1 m naoh + 0.1 m koh) solution was investigated by various electrochemicalmethods such as potentiodynamic polarization, mott–schottky analysis and electrochemical impedancespectroscopy (eis). potentiodynamic polarization curves revealed that increasing chloride ...

CD1d-restricted natural killer T cells with invariant T cell receptor α chains (iNKT cells) are a unique lymphocyte subset that responds to recognition of specific lipid and glycolipid antigens. They are conserved between mice and humans and exert various immunoregulatory functions through their rapid secretion of a variety of cytokines and secondary activation of dendritic cells, B cells and N...

the correlation between serum steroid hormones, testosterone (t), 17β-estradiol (e2), and progesterone (p) and weight of female fishes, biological characteristics of gonad (e.g. fertilization rate, fluid egg rate, gonadosomatic index , polarization index and oocyte diameter) in 10 female of the migratory population of sterlet (acipenser ruthenus) and 5 female of the migratory population of sibe...

the dependence of some thermodynamic properties of spin-polarized liquid 3he such as velocity of sound, adiabatic index, isentropic compressibility and temperature on the spin polarization has been investigated along different isentropic paths. the lennard-jones potential has been used in our calculations. it has been found that for higher values of entropy, the spin polarization has greater ef...