The concentrations of oestradiol-17beta, oestriol, and progesterone were measured in the plasma of 100 patients at the time of induction of labour by artificial rupture of membranes. There was no statistically significant difference in the hormone concentration or in the ratio of oestrogens to progesterone between patients who went into labour after rupture of the membranes and those who did no...

Induction of labour (IOL) is one of the most frequently used techniques in current obstetrics. According to WHO, 25% of all deliveries in developed countries are induced. Generally, developing countries have lower rates of IOL [1]. The goal is to get the advancement of the delivery before its spontaneous evolution. There are many controversies on this procedure and; therefore, dissimilar guides...

Oxytocin is a valuable, time-tested drug and one of the most commonly used medications during labour and delivery.1 It acts on the smooth muscle of the uterus to stimulate contractions. In Canada, its uses include the induction of labour in patients with a medical indication for the initiation of labour; the stimulation and reinforcement of labour; and to control postpartum bleeding and hemorrh...

BACKGROUND Numerous study results vary when analyzing the relationship between labor induction and the likelihood of cesarean delivery; and few have accounted for the multiple influences of maternal sociodemographic characteristics combined with the provider and hospital in subsequent birth outcomes such as cesarean section. OBJECTIVE This study evaluated the likelihood of cesarean birth foll...

OBJECTIVE To determine induction start time(s) that would maximise daytime deliveries when using prostaglandin vaginal inserts. METHODS Women enrolled into the Phase III trial, EXPEDITE (clinical trial registration: NCT01127581), had labour induced with either a misoprostol or dinoprostone vaginal insert (MVI or DVI). A secondary analysis was conducted to determine the optimal start times for...

OBJECTIVE To evaluate the effect of dexamethasone administration on labor duration. METHOD In this controlled trial 122 nulliparous women with a full-term pregnancy and a Bishop score of 7 or greater were randomly assigned to receive a single 8-mg dose of dexamethasone or placebo 6 hours before initiation of labor induction. RESULTS The interval between initiation of labor induction and beg...

At times, despite an unripe cervix, induction of labor may be needed. In these cases, a safe and suitable method should be considered for cervical ripening and pregnancy termination. The aim of this study is the comparison of vaginal misoprostol with Foley catheter for cervical ripening and induction of labor. This randomized clinical trial was performed on 108 pregnant women who had referred t...

OBJECTIVES To study the safety and efficacy of oral mifepristone in pre-induction cervical ripening and induction of labour in prolonged pregnancy. METHODS This is a single blind randomized control trial. 100 women with prolonged pregnancy beyond 40 weeks and Bishop score <6 were recruited, and randomly allocated into two groups. Women who received Tab. Mifepristone 200 mg orally were assigne...