BACKGROUND & OBJECTIVES Hot water epilepsy (HWE) is well recognized reflex epilepsy with possible genetic susceptibility. Rat model and human experimentation had proven that HWE is a type of hyperthermic seizure with possible kindling on repeated stimulation in animals. The present study was undertaken to investigate kindling associated with hyperthermic seizures induced by repeated hot water s...

PURPOSE To investigate if phenotypic variations have prognostic implications in juvenile myoclonic epilepsy (JME). METHODS Sixty-five consecutive JME patients had video-EEG recording and were followed for at least three years. Reflex traits were defined as seizures and/or EEG discharges induction by eye-closure, photic stimulation, language, praxis or calculation. Patients had psychiatric eva...

Epilepsy is a clinical syndrome caused by highly synchronized abnormal discharges of neurons in the brain. It common disease nervous system. The pathogenesis epilepsy has not been fully understood yet. main pathological changes after seizures are programmed neuronal death and glial proliferation. Autophagy catabolic process. Moderate autophagy critical to maintain homeostasis cell health, while...

Data on the epidemiology of epilepsy in a rural community in a developing country would be of value in planning a decentralized management of this malady in its early stages commensurate with available local resources. A detailed screening instrument covering various seizure types was used by trained paramedical workers in a door-to-door survey of a population of 64,963 in rural South India. Th...

[Purpose] Whole-body vibration (WBV) can induce reflex responses in muscles. A number of studies have reported that the physiological mechanisms underlying this type of reflex activity can be explained by reference to a stretch-induced reflex. Thus, the primary objective of this study was to test whether the WBV-induced muscular reflex (WBV-IMR) can be explained as a stretch-induced reflex. [Su...

We investigate the interaction between reaction-diffusion systems coupled by diffusion. The photosensitive CDIMA (chorine dioxide-iodine-malonic acid) reaction allows us to study experimentally the mutual influence of two layers of Turing patterns coupled via a diffusive interaction. By illuminating each of the layers with different intensities of homogeneous external light, the chemical condit...

PurposeJuvenile myoclonic epilepsy (JME), like other forms of idiopathic generalized epilepsy, shows a marked female predominance. However, few studies have specifically addressed the role sex in its long-term prognosis. We performed systematic review literature relevant to JME prognosis, focusing on sex-based differences prognostic factors and outcome.MethodsA comprehensive search PubMed Scopu...

Photosensitive epilepsy (PSE) is the most common form of human reflex epilepsy, appearing in up to 10% of epileptic children. It also offers a highly reproducible model to investigate whether changes in neuronal activity preceding the transition to an epileptic photoparoxysmal response (PPR) may be detected. We studied 10 patients with idiopathic PSE (eight female, mean age 26 years, range 9-51...