نتایج جستجو برای: induced apoptosis
تعداد نتایج: 1071526 فیلتر نتایج به سال:
To explore the effect and mechanism of Danggui Buxue decoction on high glucose-induced apoptotic oxidative injury in human retinal vascular endothelial cells. Human cells were treated with glucose to mimic diabetic retinopathy condition vitro. The 3-(4,5-dimethylthiazol-2- yl)-2,5-diphenyl-2H-tetrazolium bromide assay flow cytometry used investigate cell viability apoptosis. Western blot was ap...
ABSTRACT Background: Tumor cells exhibit an increased requirement for iron to support their rapid proliferation. Deferoxamine (DFO), an iron chelator, has been reported to have anti-proliferative effects on cancer cells through induction of apoptosis and cell cycle arrest. X-rays also induce apoptosis and cell cycle arrest. However, limited information is available regarding the effect of iron...
new approach of breast cancer therapy is developed toward combination therapy with agent that have a specific molecular target. our previous study showed that citrus aurantifolia lime peels ethanolic extract (cpe) increased the sensitivity of mcf-7 cells againts doxorubicin. this study aims to observe the mechanism of combination cpe and doxorubicin in cell cycle modulation and apoptosis on mcf...
Objective(s): The role of the Apoptosis repressor with caspase recruitment domain (ARC) in apoptosis and in certain hypertrophic responses has been previously investigated, but its regulation of Endothelin-1 induced cardiac hypertrophy remains unknown. The present study discusses the inhibitory role of ARC against endothelin–induced hypertrophy. Results:In present study Endothelin treated car...
Abstract A poptosis r elated protein in T GF-? s ignaling pathway (ARTS) was originally discovered cells undergoing apoptosis response to TGF-?, but ARTS also acts downstream of many other apoptotic stimuli. induces by antagonizing the anti-apoptotic proteins XIAP and Bcl-2. Here we identified pro-apoptotic Sept4/ARTS gene as a p53-responsive target gene. Ectopic p53 variety p53-inducing agents...
results a significant decrease in apoptotic cells and increase in proliferative reaction were observed in the i/r + hbo group compared to the i/r group. conclusions we demonstrated that hbo suppressed apoptosis, which caused inflammation after renal i/r, and promoted tubular cell regeneration. hbo has protective effects against aki caused by renal i/r through the inhibition of apoptosis. materi...
Effect of ginger (Zingiber officinale R.) on metiram-inhibited spermatogenesis and induced apoptosis in albino miceSaber A. Sakr, Gamal M. Badawy
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