The feasibility of imaging the inflammatory response to acute transmural myocardial infarction in man using biologically active indium-111 ("'ln)-labeled autologous leukocytes was assessed in 36 patients. Indium-111 leukocytes (approximately 500 ,tCi) were injected i.v. 18-112 hours after the onset of chest pain. Cardiac imaging was performed 24 hours later with a mobile gamma camera. Twenty-on...

OBJECTIVE To evaluate therapy with high doses of (111)Indium pentetreotide in a patient with bone metastases from a carcinoid of the pancreas. CASE REPORT A 55-Year-old male presented in November 1990 with stomach ache with dorsal irradiation. Ultrasonography and computed tomography (CT-) scans of the abdomen revealed a tumour of the tail of the pancreas and liver metastases. Histological exa...

Clinical relapse of inflammatory bowel disease is characterised by increased neutrophil migration into the intestine. The site of the neutrophil chemoattractant(s), whether luminal or mucosal, may be important since, on contact with a chemoattractant, neutrophils cause indiscriminate damage to their immediate surroundings by generating reactive oxygen species and by lysosomal enzyme release. If...

The formation of an arterial thrombus is a dynamic process that depends upon the characteristics of blood flow, the triggering substrate, and the blood components. We have developed and characterized a sensitive and specific computer-assisted nuclear scintigraphic method to study the dynamics of platelet deposition on severely damaged vessels both in vitro and in vivo in nonstenotic and stenoti...

An unsuspected annular abscess at the base of a prosthetic aortic valve in a patient with endocarditis was identified by indium-111-labeled leukocyte scintigraphy alone. This highly sensitive and specific technique expediently demonstrated the surgically proven inflammatory focus.

Laser-induced melting and resolidification of single-crystalline indium phosphide (InP) upon irradiation with 150 fs laser pulses at 800 nm has been investigated by means of real-time-reflectivity measurements with subnanosecond time resolution. Melting of the surface is observed to occur very rapidly on a time scale shorter than our experimental resolution while the lifetime of the liquid phas...

Forty-eight patients who had undergone surgical reduction of a fractured neck of femur or in whom deep vein thrombosis was suspected clinically were studied by ascending phlebography and imaging after injection of autologous indium-111-labelled platelets to assess the accuracy and value of the radioisotopic technique in diagnosing deep vein thrombosis. Imaging was performed with a wide-field ga...

Eosinophils are the major cellular effectors of allergic inflammation and represent an important therapeutic target. Although the genesis and activation of eosinophils have been extensively explored, little is known about their intravascular kinetics or physiological fate. This study was designed to determine the intravascular life span of eosinophils, their partitioning between circulating and...

InGaN epilayers with different indium concentrations have been grown on 100-nm-thick AlN/n-Si(111) template using plasma assisted molecular beam epitaxy.