Detecting intracellular calcium signaling with fluorescent calcium indicator dyes is often coupled with microscopy techniques to follow the activation state of non-excitable cells, including lymphocytes. However, the analysis of global intracellular calcium responses both at the single-cell level and in large ensembles simultaneously has yet to be automated. Here, we present a new software pack...

The lattice conditional independence (LCI) model N(C)<) is defined to be the set of all normal distributions N(O, E) on IR I such that for every pair L, M E 1<, XL and xM are conditionally independent given xLnM (ct , [AP] (1993a)). Here C)< is a ring of subsets (hence a distributive lattice) of the finite index set I such that 0, IE ".K, while for K E 1<, XK is the coordinate projection of x E...

Rapid population growth, and human activities (such as agriculture, industry, transports,...) development have increased vulnerability risk for water resources. Due to the complexity of natural processes and the numerous interactions between hydro-systems and human pressures, water quality is difficult to be quantified. In this context, we present a knowledge discovery process applied to hydrol...

the zarivar lake a freshwater lake in west of kurdistan province is home for large number of native plant and animal species therefore water quality and health of the lake are vital for conservation of these species. the present study aimed at evaluation of the zarivar lake using nsf- wqi as an indicator of water quality. wqi is a suitable tool to examine and classify spatial and temporal varia...

Animals with compact sensory systems face an encoding problem where a small number of sensory neurons are required to encode information about its surrounding complex environment. Using Caenorhabditis elegans worms as a model, we ask how chemical stimuli are encoded by a small and highly connected sensory system. We first generated a comprehensive library of transgenic worms where each animal e...

An indicator dilution method for measuring oscillatory flow in a vessel is analyzed in terms of a mixing chamber with a constant volume. For the correct measurement of mean flow, the time constant of detection of the indicator Should be very much shorter than the shortest time constant of the mixing volume. The performance of such a system was examined with a thermal indicator. Although the app...

Introduction A number of authors have investigated associations between MR vascular parameters and traditional histopathological prognostic markers. Results have varied with some studies revealing correlations while others have failed to find any associations. The aim of this work was to determine if there were any associations not only between pretreatment MR derived vascular parameters and hi...

Paper presents scientometry as a science and a fundamental instrument for determining the international value of an university as well as for the statistical evaluation of scientific research results. The impact of the research measurable through scientometric indicators is analyzed. Promoting the scientific production of universities through institutional digital repositories deals with the co...

Mouse head-fixed behaviour coupled with functional imaging has become a powerful technique in rodent systems neuroscience. However, training mice can be time consuming and is potentially stressful for animals. Here we report a fully automated, open source, self-initiated head-fixation system for mesoscopic functional imaging in mice. The system supports five mice at a time and requires minimal ...