The Geographical Indication (IG) is an Industrial Property asset that relates and distinguishes the geographic origin of a product or service. In Brazil, it can be classified as Origin (IP) Denomination (DO). This study aims to provide overview deposits Indications in from publication Law nº 9.279, May 14, 1996, Law, recognition by National Institute Intellectual (INPI) between 1996 20...

Fibrodysplasia ossificans progressiva (FOP) is a genetic disease known by its progressive bone formation in soft tissues. It has various symptoms and clinical indications; however, there are two being the most definitive for diagnosis of FOP: congenital malformed great toes and progressive heterotopic ossification. Radiographic modalities such as diagnostic x-ray, magnetic resonance imaging (MR...

Erythropoietin (EPO) is the principal haematopoietic growth factor of the red blood cell line. Its major role is to stimulate the red blood cell production. EPO synthesis by peritubular cells in the kidney is regulated by oxygen concentration and must lead adaptation of the organism to face many different physiological situations. An imbalance can lead either to anaemia or polycythemia. Synthet...

The indications for collapse therapy in the treatment of tuberculosis, simply stated, are—an active pulmonary lesion. Collapse therapy has come to the front as the most effective treatment of pulmonary tuberculosis and ahead of the older measures of rest, fresh air, diet, and climatic change. There is little difference of opinion about the effectiveness of collapse therapy as determined by clin...

Rhinoplasty is considered to be one of the most challenging procedures in otolaryngology head and neck surgery. Meticulous planning and excellent surgical skills are pre-requisites for reproducible good outcomes. More than 100 years after the first rhinoplasty, many controversies regarding indication and techniques remain unresolved. The aim of this article is to review current concepts and arg...

Neuromodulation in one form or another has been studied for decades for various disease states. Although its mechanism of action remains un-explained, numerous clinical success stories suggest it is a therapy with efficacy and durability. Controlled studies have led to the approval of sacral neuromodulation for urinary urgency and frequency, urinary retention, and urinary urge incontinence. The...

Recurrent pleural effusion, which is commonly seen in clinical practice, compromises patient quality of life, especially in patients with advanced malignant disease. The therapeutic approach to the pleural space involves a wide range of techniques, including aggressive procedures such as pleurectomy. Among such techniques, pleurodesis is the most frequently used. Pleurodesis can be induced thro...