نتایج جستجو برای: indan

تعداد نتایج: 169  

Journal: :Acta Crystallographica Section E Crystallographic Communications 2015

2012
Min Jeong Go Ka Hyun Park Hwi Hyun Lee Junseong Lee

In the title compound, C(14)H(13)NOS, the dihedral angle formed by the mean planes through the indane ring system and the thio-phene ring is 85.04 (11)°. The imine bond is located in the thio-phene plane [the S-C-C-N torsion angle is 0.00 (3)°] and an intra-molecular O-H⋯N hydrogen bond is observed.

Journal: :Molecular pharmacology 2013
Nicole H Bowens Preeti Dohare Yu-Hung Kuo Alexander A Mongin

4-(2-Butyl-6,7-dichloro-2-cyclopentyl-indan-1-on-5-yl) oxobutyric acid (DCPIB) was identified as the selective blocker of volume-regulated anion channels (VRAC). VRAC are permeable to small inorganic and organic anions, including the excitatory neurotransmitter glutamate. In recent years DCPIB has been increasingly used for probing the physiologic and pathologic roles of VRAC and was found to p...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2006
Jerome Jeanblanc Dao-Yao He Nancy N H McGough Marian L Logrip Khanhky Phamluong Patricia H Janak Dorit Ron

We recently identified a homeostatic pathway that inhibits ethanol intake. This protective pathway consists of the scaffolding protein RACK1 and brain-derived neurotrophic factor (BDNF). RACK1 translocates to the nucleus after exposure of neurons to ethanol and increases expression of BDNF (McGough et al., 2004). We also found that increasing the levels of BDNF via systemic administration of RA...

Journal: :The Journal of organic chemistry 2004
D B Ramachary K Anebouselvy Naidu S Chowdari Carlos F Barbas

Amino acids and amines have been used to catalyze three component hetero-domino Knoevenagel/Diels-Alder/epimerization reactions of readily available various precursor enones (1a-l), aldehydes (2a-p), and 1,3-indandione (3). The reaction provided excellent yields of highly substituted, symmetrical and nonsymmetrical spiro[cyclohexane-1,2'-indan]-1',3',4-triones (5) in a highly diastereoselective...

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