Purpose The authors investigate the manufacturer's choice of discount schemes in a supply chain with competing retailers. Design/methodology/approach Using game-theoretic model, build two frameworks and compare analyze effects different on performance members. Findings find that retail price (market demand) quantity scheme is always higher (lower) than market share scheme. also retailers' prefe...

Introduction: Today, the infectious wastes of hospitals are considered as a public health problem. Considering the huge amounts of hazardous wastes and the disadvantages of incinerators, we need to investigate the non-combustible devices involved in biochemical treatment. This study was carried out with the aim of evaluating the cost-effectiveness of infectious wastes devices. Materials and Me...

Motivated by the operational environment in high-tech industries, this paper examines the coordination between and when time to market and capacity marketing operations utilization are both main factors. In contrast to earlier joint lot-sizing literature which focuses on price-quantity coordination, our model captures the inter-relationship between order quantity, capacity level, and lead-time....

This article develops a dynamic game model of a supply chain consisting of one manufacturer and one retailer to study the coordination mechanism and the effect of demand disruption on the coordination mechanism, where the market demand is sensitive to retail price and service. We assume that the supplier and the retailer only know the distribution of the disrupted amount after the demand disrup...

BACKGROUND AND PURPOSE The value of screening for asymptomatic carotid stenosis has become an important issue with the recently reported beneficial effect of endarterectomy. The purpose of this study is to evaluate the cost-effectiveness of using Doppler ultrasound as a screening tool to select subjects for arteriography and subsequent surgery. METHODS A computer model was developed to simula...

Cost-effectiveness of everolimus+exemestane as compared to fulvestrant was assessed in terms of the incremental cost per life year (LY) gained, from a Portuguese National Health Service (NHS) perspective. Next to main therapeutic drug costs, other healthcare costs included costs for medical visits, complementary diagnostic procedures, surgery, inpatient visits, additional therapy and end-of-lif...