A simple method to detect the existence of multiple forms of deoxythymidine was established. With this method, the pattern of the enzyme was examined in various normal and tumor tissues. The existence of multiple forms of the enzyme was demonstrated in tumor tissues such as Yoshida sarcoma, Ehrlich ascites, Hepatoma AH 130, Sarcoma 180, and Morris Hepatomas 7793 and 7794A, but not in normal rat...

The unequivocal role of progesterone in a variety of events like ovulation, mammary gland development, establishment and maintenance of pregnancy etc are well established. Also the data are accumulating on its role in male reproductive events. In vertebrates and humans, the biological activity of progesterone is mediated by two progesterone receptor proteins PR-A and PR-B, that arise from the s...

The urinary excretion of glycosaminoglycans in 28 cases of gargoylism, embracing the Hurler, Hunter, Sanfilippo, Morquio, and Scheie syndromes (McKusick, 1966), has been examined using the cetylpyridinium chloride (CPC) turbidity test, the uronic acid/creatinine ratio, and the electrophoretic pattern of urine concentrates, as routine procedures. Ion-exchange column chromatographic techniques we...

IN A PREVIOUS STUDY of the pulmonary capillary bed in mitral valve disease,' the mean value for pulmonary diffusing capacity for carbon monoxide (DL) was found to be significantly lower than normal, in agreement with several other reports.2 7 This was due mainly to impairment of the membrane diffusing capacity (DM). Reduction in pulmonary capillary blood volume (V,) was found only in patients w...