A series of transition-metal-containing molecular "loops" and "squares" has been prepared via a directed-assembly approach and characterized. The molecular loops were prepared from the reaction of cis-(PEt(3))(2)Pt(OTf)(2) with bis(4-pyridyl)-functionalized free-base salen-type ligands. Zn(II)-metalation of the salen-type ligands in the molecular loops converts the loops to molecular squares. A...

A series of cobalt salen complexes, where salen represents an N2O2 bis-Schiff-base bis-phenolate framework, are prepared, characterised and investigated for reversible-termination organometallic mediated radical polymerisation (RT-OMRP). The salen ligands contain a cyclohexane diimine bridge and systematically altered para-substituted phenoxide moieties as a method to examine the electronic imp...

Finding the energy minima of systems with constraints is a challenging problem. We develop a minimization method based on the projection operator technique to enforce distance and angle constraints in minimization and reaction-path dynamics. The application of the projection operator alone does not maintain the constraints, i.e., they are slightly violated. Therefore, we use the SHAKE-methodolo...

To understand the relationship between DNA damage potential and biochemical activities, we synthesized nine different Fe(III)-salen derivatives with varying substituents, and analyzed their in vitro DNA cleavage properties and biochemical effects on cultured human cells. Our results demonstrated that Fe(III)-salen complexes affect cell viability, induce nuclear fragmentation, and activate caspa...

Salen-type mononuclear lanthanide complexes with formula (Et3NH)[Ln(3-NO2-salen)2]·solvent (Ln = Eu (1Eu), Tb (2Tb), Dy (3Dy), Ho (4Ho), Er (5Er), Yb (6Yb); 3-NO2-salen(2-) = N,N'-bis(3-nitro-salicylaldehyde)ethylenediamine dianion) are reported. These compounds are isostructural in which two crystallographically distinct 3-NO2-salen(2-) act as tetradentate ligands encapsulating the lanthanide ...