The first study of the aphid fauna from Chukotka Autonomous Okrug has been made; 18 species are reported from this territory, the most north-eastern of Russia and of the Palaeartic Region. Five new species are described: Aphis aquilonalis sp. nov. on Rumex arcticus Trautv.; Aphis beringiensis sp. nov. were collected by yellow trap; Macrosiphoniella (Asterobium) jaroslavi sp. nov. on Artemisia a...

Promotion of germination by red light fails after prolonged dark imbibition of Rumex crispus L. seeds, indicative of a secondary dormancy. The degree and rate of inception of the dormancy increases with increasing temperature. Following establishment of the dormancy, germination response to red light can be restored by either prolonged cold treatment or brief high temperature shifts. Loss of ph...

background :   imipenem-resistant gram negative bacteria, resulting from metallo-beta-lactamase (mbls)-producing strains have been reported to be among the important causes of nosocomial infections and of serious therapeutic problem worldwide. because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzymes can confer resistance to almost all beta-lactams....

drug utilization evaluation (due) studies are designed to assess drug usage appropriateness. we aim to evaluate the drug utilization of intravenous ciprofloxacin and imipenem, two of the broad spectrum antibiotics that consume a significant proportion of our hospitals’ outlay, in different wards of a teaching hospital in zabol. during a 5 months period (december 2010 to may 2011), 263 patients ...

background: resistant strains of pseudomonas aeruginosa to imipenem was medical treatment problem, especiallyin burnt units of hospitals. objectives: this study was conducted to evaluate the antimicrobial effect of fe2o3 nanoparticles alone and functionalized with imipenem on p. aeruginosa starins producing metallo b-lactamases (mbl).materials and methods: a disk diffusion method was used to is...

We investigated the mechanisms involved in imipenem resistance in 23 clinical strains of Acinetobacter baumannii. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis showed the presence of a 30-kDa protein in imipenem-intermediate A. baumannii (IIAB) and imipenem-resistant A. baumannii (IRAB) strains; this protein was almost undetectable in imipenem-susceptible A. baum...

The mechanism of interaction between imipenem and HSA was investigated by various techniques like fluorescence, UV.vis absorbance, FRET, circular dichroism, urea denaturation, enzyme kinetics, ITC, and molecular docking. We found that imipenem binds to HSA at a high affinity site located in subdomain IIIA (Sudlow's site I) and a low affinity site located in subdomain IIA.IIB. Electrostatic inte...

Two new naphthalene acylglucosides, rumexneposides A (1) and B (2), together with 12 known compounds (3-14), were isolated from the roots of Rumex nepalensis. Their structures were established by chemical and spectroscopic methods. The biological activities of compounds 1-14 as well as an additional 11 compounds previously isolated from R. nepalensis and Rumex hastatus (15–25) were evaluated ag...