The direct insertion of nitriles into zirconocene-1-aza-1,3-diene complexes provides an efficient, chemoselective, and controllable synthesis of N-H and N-substituted pyrroles upon acidic aqueous work-up. The outcome of the reaction (that is, the formation of N-H or N-substituted pyrroles) results from the different cyclization patterns, which depend on the relative stability and reactivity of ...

A one-pot, three-minute, gram-scale synthesis of novel sp3-nanocrystalline, water-soluble, and fluorescent carbon dots (FCDs), from simple and cheap sugar starting materials is described. Mechanism studies showed that NH2-FCD formation proceeds via a crucial imine intermediate derived from reaction between a sugar hemiacetal and an amine. Moreover, we successfully demonstrate the utility of lac...

The mol-ecule of the title compound, C(16)H(23)N(3)O(5), is twisted about the chiral C atom, the dihedral angle formed between the amide residues being 79.6 (3)°. The conformation about the imine bond [1.278 (5) Å] is E. In the crystal, O-H⋯O and N-H⋯O hydrogen bonding between the hy-droxy, amine and carbonyl groups leads to the formation of supra-molecular layers, which stack along the c-axis ...

Chiral ferrocene-based phosphine-imine ligands 1–3 and sulfur-imine ligand 4 were applied in the palladium-catalyzed asymmetric allylic alkylation of cycloalkenyl esters. The results revealed that the substitutents in aryl ring, ferrocenylmethyl and benzyliene position strongly affected the enantioselective induction of phosphine-imine ligands, and the most stereoselective ligand was ferrocenyl...

Relational database management systems manages the tables with predefined indexes. In RDBMS indexes are created on the basis of attribute values. The Imine indexing scheme is used to index item sets in relational databases. The index creation is performed with out any constraints. IMine provides a complete representation of the original database. The Imine indexing scheme reduces the input/outp...

In order to suggest detailed mechanistic hypotheses for the formation and dehydration of a key carbinolamine intermediate in the T4 pyrimidine dimer glycosylase (T4PDG) reaction, we have investigated these reactions using steered molecular dynamics with a coupled quantum mechanics-molecular mechanics potential (QM/MM). We carried out simulations of DNA abasic site carbinolamine formation with a...

Relational database management systems manages the tables with predefined indexes. In RDBMS indexes are created on the basis of attribute values. The Imine indexing scheme is used to index item sets in relational databases. The index creation is performed with out any constraints. IMine provides a complete representation of the original database. The Imine indexing scheme reduces the input/outp...