there are confirmed beneficiary effects of exercise on atherosclerotic inflammation of ischemia-associated heart diseases. the purpose of this study was to evaluate the effect of aerobic exercise on t-regulatory cell markers of il-35 as well as foxp3 and t-helper2 marker of il-33 in patients with ischemic heart disease (ihd). this research was performed on 44 asymptomatic male patients with isc...

Interleukin-1 family 7 (IL-1F7) is a novel member of IL-1F cytokines. IL-1F7 is more commonly known as IL-37. IL-37 join the α-subunit of the IL-18 receptor, or IL-18 binding protein (IL-18BP), and binding of these proteins can enhance the IL-18 suppression. IL-37 also translocates to the cell nucleus and affects gene transcription. IL-37 inhibits the phosphorylation of p38 mitogen-activated pr...

We consider commutative string rewriting systems (Vector Addition Systems, Petri nets), i.e., string rewriting systems in which all pairs of letters commute. We are interested in reachability: given a rewriting system R and words v and w, can v be rewritten to w by applying rules from R? A famous result states that reachability is decidable for commutative string rewriting systems. We show that...

This paper uses the theory of dual equivalence graphs to give explicit Schur expansions for several families of symmetric functions. We begin by giving a combinatorial definition of the modified Macdonald polynomials and modified HallLittlewood polynomials indexed by any diagram δ ⊂ Z × Z, written as H̃δ(X; q, t) and H̃δ(X; 0, t), respectively. We then give an explicit Schur expansion of H̃δ(X; 0,...

background: interleukin-27 is a heterodimeric cytokine belonging to il-12 and il-23 families, secreted  by antigen presenting cells( apcs ) .the il-27 is composed of 2 subunits: epstein-barr virus induced gene 3 (ebi3) and p28. il-27 is an anti-inflammatory cytokine which has an inhibitory effect on th17 population and suppress the il-17 expression. it is suggested that il-27 could be a potent ...

Genetic and epigenetic factors are considered to be critical for host-parasite interactions. There limited data on the role of such during human infections with Ascaris lumbricoides . Here, we describe potential genetic as determinants Th2 immune response A. in Brazilian children. Stool samples were collected from children detect by microscopy peripheral blood leukocytes (PBLs) cultured whole c...

sleep plays a vital role in regulating physiological mechanisms in the human body. nowadays, by the change of lifestyle and as a consequence of longer work hours and increased accessibility to media, sleep disturbance becomes a common problem in modern society. many studies demonstrated that sleep disturbance triggers a systemic low-grade inflammation by increasing the level of several cytokine...

Background: Cytokines are cell signaling molecules which upon release by cells facilitate the recruitment of immune-modulatory cells towards the sites of inflammation. Genetic variations in cytokine genes are shown to regulate their production and affect the risk of infectious as well as autoimmune diseases. Intron-3 of interleukin-4 gene (IL-4) harbors 70-bp variable number of tandem repeats (...

The intron-exon structure of Khorasan native fowl interleukin-2 (IL-2) was investigated. For this purpose, twenty chickens were selected from the Native Fowl Breeding Station of Khorasan province, and genomic DNA was extracted using a modified conventional DNA extraction protocol. An 875 bp fragment of IL-2 was successfully amplified, including a small part of the promoter, exon 1, intron 1, an...