نتایج جستجو برای: il 13

تعداد نتایج: 462785  

Journal: :The Journal of biological chemistry 2002
Allison-Lynn Andrews John W Holloway Sarah M Puddicombe Stephen T Holgate Donna E Davies

Interleukin (IL)-13 is a key cytokine associated with the asthmatic phenotype. It signals via its cognate receptor, a complex of IL-13 receptor alpha1 chain (IL-13Ralpha1) with IL-4Ralpha; however, a second protein, IL-13Ralpha2, also binds IL-13. To determine the binding contributions of the individual components of the IL-13 receptor to IL-13, we have employed surface plasmon resonance and eq...

Journal: :Journal of Allergy and Clinical Immunology 2021

Journal: :Journal of Investigative Dermatology 2023

Type 2 cytokines, especially IL-4 and IL-13, play central roles in the pathogenesis of atopic dermatitis (AD). Immune cells acquired immunity Th2 cells, innate immune such as group lymphoid (ILC2s) basophils are major source type cytokines AD lesions. It is well known that alarmins including thymic stromal lymphopoietin (TSLP), IL-33, IL-25 essential activation cells. However, it not clear whet...

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