le mouvement transversal de la locomotive ou des wagons , appele ie lacet, provient de deux causes principales: -la conicite des bandages -les irregularites de la voie dans ie plan horizontal. on se propose ici d'etudier la premiere cause , ce qui nous conduit a une equation differentielle non lineaire du deuxieme ordre. • l'equation en question est etudiee dans plusieurs cas difftten...

We design and release BONIE, the first open numerical relation extractor, for extracting Open IE tuples where one of the arguments is a number or a quantity-unit phrase. BONIE uses bootstrapping to learn the specific dependency patterns that express numerical relations in a sentence. BONIE’s novelty lies in task-specific customizations, such as inferring implicit relations, which are clear due ...

Active cytomegalovirus (CMV) infection was treated successfully by only CMV antibody-enriched immunoglobulin (CMV-IG) in a renal transplant recipient. CMV-IG was injected at 86 mg/kg i.v. twice a day for a total of 16 days (4 plus 12 days, interrupted by a pause of 4 days), followed by weekly i.v. injection of 86 mg/kg (7 weeks). Active CMV infection was diagnosed on the basis of DNAemia in pla...

Subunit vaccines formulated with purified fusion proteins from the A2 (PFP-2) or attenuated 248/404 (PFP-3) strains of respiratory syncytial virus (RSV) were evaluated, either alone or in combination with native attachment (G) protein, for their ability to augment serum neutralizing antibody titers in seropositive chimpanzees. The results suggested that combination vaccines enhanced serum neutr...

Nomifensine (Mental. Alival; Hoechst. Frankfurt. FRG). an antidepressant drug. may cause immune hemolytic anemia (IHA) of the so-called immune complex type that is believed to occur by means of an innocent-bystander mechanism. In this report we describe findings that are not consistent with this mechanism in a patient with nomifensine-induced intravascular IHA associated with renal failure. In ...

Traditionally, heat shock proteins (HSPs) are believed to be located intracellularly, where they perform a variety of chaperoning functions. Recently, evidence has accumulated that some tumor cells express HSPs on the cell surface. The present study confirms this finding and correlates HSP72 cell surface expression, induced by nonlethal heat shock, with an increased sensitivity to interleukin-2...

JEM © The Rockefeller University Press $30.00 Vol. 205, No. 4, April 14, 2008 967-979 www.jem.org/cgi/doi/ 967 10.1084/jem.20072051 Rheumatoid arthritis (RA) is a chronic disease aff ecting the peripheral joints in which abnormalities in the synovium precipitate a destructive process that often leads to cartilage and bone erosion. The autoimmune nature of this disease has been defi ned, in part...

86 NATURE | VOL 402 | 4 NOVEMBER 1999 | www.nature.com Calculation of correlated mRNA expression Results of 97 individual publicly available DNA chip yeast mRNA expression data sets were encoded as a string of 97 numbers associated with each yeast open reading frame (ORF) describing how the mRNA of that ORF changed levels during normal growth, glucose starvation, sporulation and expression of m...

conclusions endocarditis is an important disease with a high mortality rate if not treated appropriately. therefore, these patients need more attention. in echocardiography, vegetation and complications of ie such as abscess and paravalvular leakage can be detected. results we studied 35 patients, 45% male and 55% female with a mean age of 56.36 ± 12.44 years. fever (80%) and chills (65.7%) wer...

Hepatitis A virus (HAV) immunoassays use cell culture-derived HAV antigen to detect HAV-specific antibodies. The current method of production of HAV antigen in tissue culture is time-consuming and expensive. We previously expressed the HAV open reading frame in recombinant vaccinia viruses (rV-ORF). The recombinant HAV polyprotein was accurately processed and was assembled into subviral particl...