Apolipoproteins E and C-III are modulators of lipoprotein metabolism that could affect development of atherosclerosis. The prevalence in plasma of apoB-containing particles (LpB) that contain either apoE or apoC-III, both or neither, and the effect of estrogen on these lipoproteins are unknown. The LpB particle system, defined by the presence or absence of apoE or C-III, was studied in 13 normo...

Some patients with coronary artery disease experience continued progression of one or more coronary lesions despite treatment with drugs that inhibit 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and markedly lower plasma cholesterol levels. We examined relationships between the progression of coronary artery lesions and plasma lipoproteins, in particular intermediate density lipopro...

CORBA is a standard proposed by the Object Management Group (OMG) in order to promote interoperability between distributed object systems. CORBA provides a programming-language neutral Interface Definition Language (IDL) that describes the syntactic aspects of services supported by remote objects. However, CORBA IDL does not provide any means to specify the behaviour of objects in an abstract a...

The future of distributed client/server computing will consist of the WWW and Corba environments. First, the WWW is the user-friendly uniform interface to access any distributed resource. Second, Corba is a single uniform object-oriented view of distributed and heterogeneous systems integration. Then these two worlds need to merge to make distributed objects user-friendly. This paper rst presen...

This research concerns the metabolism of apolipoprotein B (apoB) in hypertriglyceridemic subjects with polydisperse or heterogeneous LDL. Five subjects maintained under constant dietary control had blood samples fractionated into very low density lipoprotein (VLDL), Sf 20, Sf 10, and Sf 4 LDL, and plasma free leucine, and in three subjects VLDL was further fractionated by size. Apo B was isolat...

The International Database of Longevity (IDL) offers detailed information on thoroughly validated cases of supercentenarians. These data are used to estimate human mortality after age 110. The procedure properly accounts for the country-specific sampling frames in the IDL. The analysis confirms that human mortality after age 110 is flat at a level corresponding to an annual probability of death...

Background Plasma non-high-density lipoproteins impact development of central arterial stiffness and cerebral small vessel disease (cSVD), significantly contributing to Alzheimer’s (AD) related dementias (ADRDs) through an increase in amyloid beta (Aβ) burden acceleration atrophy susceptible brain regions. We sought identify proteins three non-HDL plasma (very-low density lipoprotein [VLDL], in...

Traditional IDLs were defined for describing the services that objects offer, but not those services they require from other objects, nor the partial ordering in which they expect their methods to be used. In this paper we propose an extension of the CORBA IDL that uses a sugared subset of the polyadic π-calculus for describing object service protocols, aimed towards the automated checking of p...

An increasing number of systems have a distributed software architecture. The main focus of this paper is on OMG/CORBA, a widely recognized middleware standard for heterogeneous and distributed system construction. We discuss CORBA’s object model and its representation in the OMG interface definition language (IDL). We show how distributed system components written in different programming lang...

An increasing number of applications are now being developed in a distributed setting. The main focus of this half-day tutorial is on OMG/CORBA, a widely recognised middleware standard for heterogeneous and distributed application integration. The tutorial discusses CORBA's object model and its representation in the OMG interface de nition language (IDL). Programming language bindings to IDL ar...