Background: Children with idiopathic thrombocytopenic purpura who are treated with intravenous immunoglobulin therapy might experience a decline in their absolute neutrophil count. The aim of this study was to investigate the incidence of neutropenia following intravenous immunoglobulin therapy in children with idiopathic thrombocytopenic purpura undergoing intravenous immunoglobulin therapy. ...

bakcground: the aim of itp treatment is to prevent intracranial hemorrhage and increase the platelet count rapidly. this study was conducted with the objective of comparing the efficacy of anti-d immunoglobulin (ig) with dexamethasone in treating childhood itp. materials and methods: in this randomized prospective control trial, 20 itp patients (platelet count< 20,000/µl) younger than 16 were s...

background: children with idiopathic thrombocytopenic purpura who are treated with intravenous immunoglobulin therapy might experience a decline in their absolute neutrophil count. the aim of this study was to investigate the incidence of neutropenia following intravenous immunoglobulin therapy in children with idiopathic thrombocytopenic purpura undergoing intravenous immunoglobulin therapy. p...

mental stress and daily crises comprise a part of physical and mental threats. perceived stress is a physical and mental threat, as well. perceived stress is a psychological process during which the individual considers his/ her physical and psychological welfare as being threatened. since idiopathic thrombocytopenic purpura (itp) is one of the chronic diseases being able to affect patients' pe...

immune thrombocytopenic  purpura (itp) is an autoimmune bleeding disorder characterized by production  of auto-antibodies against platelet antigens. it is obvious that regulatory t cells (tregs) have a major role in controlling immune homeostasis and preventing autoimmunity. to investigate the frequency and functions of tregs, twenty itp patients and twenty age- and sex- matched healthy control...

CCUMULATION of lipid, presumably phospholipid, in histiocytes of the splenic cords has been seen in association with thrombocytopenic purpura in six patients operated on in Barnes Hospital. At the time that each of the first four were examined, a diagnosis or description of lipid histiocytosis of the spleen was made, but after that the constant association with thrombocytopenic purpura was note...

Idiopathic thrombocytopenic purpura (ITP) is characterized by a low platelet count, which is the result of both increased platelet destruction and insufficient platelet production. Although the development of autoantibodies against platelet glycoproteins remains central in the pathophysiology of ITP, several abnormalities involving the cellular mechanisms of immune modulation have been identifi...

We studied the extent to which patient characteristics influenced outcome in childhood idiopathic thrombocytopenic purpura in a historical cohort of 289 children over a 20 year period (1968-87). Outcome was classified as acute or chronic depending on whether the platelet count had returned to normal (150 X 10(9)/l) by six months after diagnosis. Fifty three cases (18%) had chronic idiopathic th...