background: idiopathic thrombocytopenic purpura (itp) is a chronic disease which is accompanied with hopelessness and loss of the sense of well-being due to its symptoms and treatment. it also affects patients' sense of social and spiritual well-being. this disorder decreases patients' self-esteem and their quality of life by changing their mental image and self-confidence. this study was perfo...

Idiopathic thrombocytopenic purpura, an immune-mediated disease, usually has a relatively benign clinical course. Bleeding manifestations are mostly mucocutaneous and mild. Massive haemorrhages requiring transfusions or other interventions are rare, unless platelet counts are extremely low or other complicating conditions coexist. The rupture of an ovarian follicle is a very common benign condi...

The mechanisms of platelet destruction and their sites of sequestration in disease states are poorly understood. Although recent studies have emphasized the importance of platelet isoantibodies in certain clinical situations (1-3), little is known of the effects of antibodies on platelets in vivo. In conditions such as idiopathic thrombocytopenic purpura, there is debate as to whether immune me...

Idiopathic thrombocytopenic purpura (ITP) is the most common acquired bleeding disorder in childhood. ITP is characterized by a lo� circulating platelet count caused principally by destruction of antibody-coated platelets in the reticuloendothelial system. It can be classified into t�o major forms, acute and chronic. Acute ITP is usually a benign self-limiting condition �ith a high probability ...

ITP is the most common autoimmune disease during pregnancy. Whereas the maternal risk due to the extreme thrombocytopenia can be calculated, the risk to the foetus is difficult to predict. As there is no correlation between maternal and foetal platelet count, no generalisations can be made as to the preferable method of delivery. The methods of treatment with special reference to pregnancy and ...

Purpura is a relatively common symptom in childhood and may be due to a variety of causes. A platelet count enables one to exclude the nonthrombocytopenic variety, but more elaborate investigations are needed to exclude other primary conditions which are often associated with thrombocytopenia, e.g. leukaemia. There remains a group of patients with idiopathic thrombocytopenic purpura and it is w...

CCUMULATION of lipid, presumably phospholipid, in histiocytes of the splenic cords has been seen in association with thrombocytopenic purpura in six patients operated on in Barnes Hospital. At the time that each of the first four were examined, a diagnosis or description of lipid histiocytosis of the spleen was made, but after that the constant association with thrombocytopenic purpura was note...

Sir, Here we report an interesting case of idiopathic thrombocytopenic purpura (ITP). The case was a male patient born in 1925. He was healthy until he manifested epistasis and proteinuria in 1975. At that time, his platelet count was 0.5310umm. Bone marrow examination revealed normal haematopoiesis with normal megakaryocyte number, consistent with ITP. Anti-DNA antibodies were negative. Renal ...

Thrombotic thrombocytopenic purpura is a rare but serious condition in childhood. It can be idiopathic or a complication of other diseases or drug therapy. We report on a 12-year-old Chinese girl who presented with fulminant systemic lupus erythematosus with progressive renal failure, pancytopenia, and cerebral dysfunction due to thrombotic thrombocytopenic purpura. The patient also had Pneumoc...