We analyse the spatial distribution and colour of the intracluster light (ICL) in 683 clusters of galaxies between z = 0.2 and 0.3, selected from ∼ 1500 deg of the first data release of the Sloan Digital Sky Survey (SDSS-DR1). Surface photometry in the g, r and i bands is conducted on stacked images of the clusters, after rescaling them to the same metric size and masking out resolved sources. ...

The retinal pigment epithelium (RPE) regulates the ionic composition of the fluid surrounding the photoreceptors by transport mechanisms that utilize Cl- channels. Cl- currents in RPE cells, however, remain incompletely characterized. The purpose of this study was to identify the Cl- currents in acutely isolated Xenopus RPE cells using whole-cell patch clamp. We describe three different Cl- cur...

Calcium (Ca(2+))-activated chloride (Cl(-)) channels (CaCCs) play a role in the modulation of action potentials and synaptic responses in the somatodendritic regions of central neurons. In the vertebrate retina, large Ca(2+)-activated Cl(-) currents (ICl(Ca)) regulate synaptic transmission at photoreceptor terminals; however, the molecular identity of CaCCs that mediate ICl(Ca) remains unclear....

The independent choice logic (ICL) is part of a project to combine logic and decision/game theory into a coherent framework. The ICL has a simple possible-worlds semantics characterised by independent choices and an ac yclic logic program that specifies the consequences of these choices. This paper gives an abductive characterization of the ICL. The ICL is defined model-theoretically, but we sh...

Mono-ubiquitination of Fancd2 is essential for repairing DNA interstrand cross-links (ICLs), but the underlying mechanisms are unclear. The Fan1 nuclease, also required for ICL repair, is recruited to ICLs by ubiquitinated (Ub) Fancd2. This could in principle explain how Ub-Fancd2 promotes ICL repair, but we show that recruitment of Fan1 by Ub-Fancd2 is dispensable for ICL repair. Instead, Fan1...

We are undertaking a program to measure the characteristics of the intracluster light (total flux, profile, color, and substructure) in a sample of 10 galaxy clusters with a range of cluster mass, morphology, and redshift. We present here the methods and results for the first cluster in that sample, A3888. We have identified an intracluster light (ICL) component in A3888 in V and r that contain...

DNA interstrand cross-links (ICLs) are induced by many carcinogens and anitcancer drugs. ICL is a covalent linkage of both strands of DNA, preventing DNA strand separation during transcription and replication; thus, it is extremely cytotoxic in vivo. Psoralen and its derivatives are widely applied for the clinical treatment of several skin diseases and cutaneous T cell lymphoma, and they are al...